Cargando…

Human pluripotent stem cell-derived alveolar epithelial cells are alternatives for in vitro pulmotoxicity assessment

Human pluripotent stem cell (hPSC)-derived alveolar epithelial cells (AECs) provide new opportunities for understanding lung development and the treatment of pulmonary diseases. However, toxicity assessments using hPSC-AECs have not been undertaken. In this study, we generated functional AECs from h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heo, Hye-Ryeon, Kim, Jeeyoung, Kim, Woo Jin, Yang, Se-Ran, Han, Seon-Sook, Lee, Seong Joon, Hong, Yoonki, Hong, Seok-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346100/ https://www.ncbi.nlm.nih.gov/pubmed/30679658 http://dx.doi.org/10.1038/s41598-018-37193-3

Ejemplares similares

Cadmium-induced ER stress and inflammation are mediated through C/EBP–DDIT3 signaling in human bronchial epithelial cells
por: Kim, Jeeyoung, et al.
Publicado: (2017)

ACN9 Regulates the Inflammatory Responses in Human Bronchial Epithelial Cells
por: Jeong, Jae Hoon, et al.
Publicado: (2017)

Generation of macrophage containing alveolar organoids derived from human pluripotent stem cells for pulmonary fibrosis modeling and drug efficacy testing
por: Heo, Hye-Ryeon, et al.
Publicado: (2021)

Diesel Particulate Matter 2.5 Induces Epithelial-to-Mesenchymal Transition and Upregulation of SARS-CoV-2 Receptor during Human Pluripotent Stem Cell-Derived Alveolar Organoid Development
por: Kim, Jung-Hyun, et al.
Publicado: (2020)

Reprogramming mechanisms influence the maturation of hematopoietic progenitors from human pluripotent stem cells
por: Heo, Hye-Ryeon, et al.
Publicado: (2018)

Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway
por: Kim, Hye-Ryun, et al.
Publicado: (2016)

Human Pluripotent Stem Cell-Derived Alveolar Epithelial Cells as a Tool to Assess Cytotoxicity of Particulate Matter and Cigarette Smoke Extract
por: Kim, Jung-Hyun, et al.
Publicado: (2022)

Inhibition of MicroRNA-221 and 222 Enhances Hematopoietic Differentiation from Human Pluripotent Stem Cells via c-KIT Upregulation
por: Lee, Ji Yoon, et al.
Publicado: (2018)

Human pluripotent stem-cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing
por: Kim, Jung-Hyun, et al.
Publicado: (2021)

Plasma CRABP2 as a Novel Biomarker in Patients with Non-Small Cell Lung Cancer
por: Kim, Do Jun, et al.
Publicado: (2018)

Hormonal Regulation of Hematopoietic Stem Cells and Their Niche: A Focus on Estrogen
por: Heo, Hye-Ryeon, et al.
Publicado: (2015)

BMP4 and perivascular cells promote hematopoietic differentiation of human pluripotent stem cells in a differentiation stage-specific manner
por: Jeong, Suji, et al.
Publicado: (2020)

Paracrine influence of human perivascular cells on the proliferation of adenocarcinoma alveolar epithelial cells
por: Kim, Eunbi, et al.
Publicado: (2017)

Regulation of JAM2 Expression in the Lungs of Streptozotocin-Induced Diabetic Mice and Human Pluripotent Stem Cell-Derived Alveolar Organoids
por: Rasaei, Roya, et al.
Publicado: (2020)

Human pluripotent stem cell-derived macrophages and macrophage-derived exosomes: therapeutic potential in pulmonary fibrosis
por: Rasaei, Roya, et al.
Publicado: (2022)

Word Embedding Reveals Cyfra 21-1 as a Biomarker for Chronic Obstructive Pulmonary Disease
por: Heo, Jeongwon, et al.
Publicado: (2021)

Sex differences of COPD phenotypes in nonsmoking patients
por: Hong, Yoonki, et al.
Publicado: (2016)

Bleomycin Inhibits Proliferation via Schlafen-Mediated Cell Cycle Arrest in Mouse Alveolar Epithelial Cells
por: Jang, Soojin, et al.
Publicado: (2019)

A cluster analysis of chronic obstructive pulmonary disease in dusty areas cohort identified three subgroups
por: Kim, Suhyun, et al.
Publicado: (2017)

Human Pluripotent Stem Cell-Derived Alveolar Organoid with Macrophages
por: Seo, Ha-Rim, et al.
Publicado: (2022)

Modeling fibrotic alveolar transitional cells with pluripotent stem cell-derived alveolar organoids
por: Ptasinski, Victoria, et al.
Publicado: (2023)

Perivascular Stem Cells Suppress Inflammasome Activation during Inflammatory Responses in Macrophages
por: Kim, Jeeyoung, et al.
Publicado: (2019)

In Vitro Culture-Induced Pluripotency of Human Spermatogonial Stem Cells
por: Lim, Jung Jin, et al.
Publicado: (2013)

Exploration of Alternative Splicing Events in Mesenchymal Stem Cells from Human Induced Pluripotent Stem Cells
por: Jeong, Ji-Eun, et al.
Publicado: (2021)

Identification of Alternative Splicing and Fusion Transcripts in Non-Small Cell Lung Cancer by RNA Sequencing
por: Hong, Yoonki, et al.
Publicado: (2016)

Generation of human alveolar epithelial type I cells from pluripotent stem cells
por: Burgess, Claire L, et al.
Publicado: (2023)

Glyoxalase 1 as a Therapeutic Target in Cancer and Cancer Stem Cells
por: Kim, Ji-Young, et al.
Publicado: (2022)

Generation of PDGFRα(+) Cardioblasts from Pluripotent Stem Cells
por: Hong, Seon Pyo, et al.
Publicado: (2017)

Levels of vitamin D-associated cytokines distinguish between active and latent tuberculosis following a tuberculosis outbreak
por: Hong, Yoonki, et al.
Publicado: (2019)

Therapeutic effects of adipose-derived stem cells pretreated with pioglitazone in an emphysema mouse model
por: Hong, Yoonki, et al.
Publicado: (2016)

Tuberculosis-Infected Giant Bulla Treated by Percutaneous Drainage Followed by Obliteration of the Pulmonary Cavity Using Talc: Case Report
por: Heo, Jeongwon, et al.
Publicado: (2021)

Successful treatment of disseminated interdigitating dendritic cell sarcoma with adriamycin, bleomycin, vinblastine, and dacarbazine chemotherapy
por: Lee, Suk-young, et al.
Publicado: (2012)

Changes in the Characteristics and Long-term Mortality Rates of Intensive Care Unit Patients from 2003 to 2010: A Nationwide Population-Based Cohort Study Performed in the Republic of Korea
por: Heo, Jeongwon, et al.
Publicado: (2018)

In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells
por: van Riet, Sander, et al.
Publicado: (2020)

Generation of Alveolar Epithelial Spheroids via Isolated Progenitor Cells from Human Pluripotent Stem Cells
por: Gotoh, Shimpei, et al.
Publicado: (2014)

Low-dose nivolumab can be effective in non-small cell lung cancer: alternative option for financial toxicity
por: Yoo, Shin Hye, et al.
Publicado: (2018)

Sinapic Acid Controls Inflammation by Suppressing NLRP3 Inflammasome Activation
por: Lee, Eun Hye, et al.
Publicado: (2021)

MicroRNA-22 enhances the differentiation of mouse induced pluripotent stem cells into alveolar epithelial type II cells
por: Tao, Fan, et al.
Publicado: (2020)

Differentiation of human induced pluripotent stem cells into functional lung alveolar epithelial cells in 3D dynamic culture
por: Alsobaie, Sarah, et al.
Publicado: (2023)

Long-Term Expansion of Functional Human Pluripotent Stem Cell-Derived Hepatic Organoids
por: Mun, Seon Ju, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pio7b51i5jpe9gckr4f1pv08a0