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Characterization of the Mode of Action of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis

Recent work has demonstrated that the polyketide natural product Aurodox from Streptomyces goldiniensis is able to block the pathogenesis of the murine pathogen Citrobacter rodentium. In this work, we aimed to gain a better understanding of the mechanism of action of the compound. We show that Aurod...

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Detalles Bibliográficos
Autores principales:	McHugh, Rebecca E., O’Boyle, Nicky, Connolly, James P. R., Hoskisson, Paul A., Roe, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Bacterial Infections
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346137/ https://www.ncbi.nlm.nih.gov/pubmed/30455200 http://dx.doi.org/10.1128/IAI.00595-18

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