Whole-Genome Sequencing of the Fungus Penicillium citrinum Reveals the Biosynthesis Gene Cluster for the Mycotoxin Citrinin

Penicillium citrinum is a food-contaminating ascomycete that consistently produces large amounts of the mycotoxin citrinin. Citrinin exhibits, besides its toxicity, antibiotic effects and thus potentially forces antibiotic resistance. Within the genome sequence, we identified the biosynthesis gene c...

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Detalles Bibliográficos
Autores principales: Schmidt-Heydt, Markus, Stoll, Dominic, Geisen, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346185/
https://www.ncbi.nlm.nih.gov/pubmed/30701236
http://dx.doi.org/10.1128/MRA.01419-18
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author Schmidt-Heydt, Markus
Stoll, Dominic
Geisen, Rolf
author_facet Schmidt-Heydt, Markus
Stoll, Dominic
Geisen, Rolf
author_sort Schmidt-Heydt, Markus
collection PubMed
description Penicillium citrinum is a food-contaminating ascomycete that consistently produces large amounts of the mycotoxin citrinin. Citrinin exhibits, besides its toxicity, antibiotic effects and thus potentially forces antibiotic resistance. Within the genome sequence, we identified the biosynthesis gene cluster for citrinin, which appears to be highly conserved within the genus Penicillium.
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spelling pubmed-63461852019-01-30 Whole-Genome Sequencing of the Fungus Penicillium citrinum Reveals the Biosynthesis Gene Cluster for the Mycotoxin Citrinin Schmidt-Heydt, Markus Stoll, Dominic Geisen, Rolf Microbiol Resour Announc Genome Sequences Penicillium citrinum is a food-contaminating ascomycete that consistently produces large amounts of the mycotoxin citrinin. Citrinin exhibits, besides its toxicity, antibiotic effects and thus potentially forces antibiotic resistance. Within the genome sequence, we identified the biosynthesis gene cluster for citrinin, which appears to be highly conserved within the genus Penicillium. American Society for Microbiology 2019-01-24 /pmc/articles/PMC6346185/ /pubmed/30701236 http://dx.doi.org/10.1128/MRA.01419-18 Text en Copyright © 2019 Schmidt-Heydt et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Genome Sequences
Schmidt-Heydt, Markus
Stoll, Dominic
Geisen, Rolf
Whole-Genome Sequencing of the Fungus Penicillium citrinum Reveals the Biosynthesis Gene Cluster for the Mycotoxin Citrinin
title Whole-Genome Sequencing of the Fungus Penicillium citrinum Reveals the Biosynthesis Gene Cluster for the Mycotoxin Citrinin
title_full Whole-Genome Sequencing of the Fungus Penicillium citrinum Reveals the Biosynthesis Gene Cluster for the Mycotoxin Citrinin
title_fullStr Whole-Genome Sequencing of the Fungus Penicillium citrinum Reveals the Biosynthesis Gene Cluster for the Mycotoxin Citrinin
title_full_unstemmed Whole-Genome Sequencing of the Fungus Penicillium citrinum Reveals the Biosynthesis Gene Cluster for the Mycotoxin Citrinin
title_short Whole-Genome Sequencing of the Fungus Penicillium citrinum Reveals the Biosynthesis Gene Cluster for the Mycotoxin Citrinin
title_sort whole-genome sequencing of the fungus penicillium citrinum reveals the biosynthesis gene cluster for the mycotoxin citrinin
topic Genome Sequences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346185/
https://www.ncbi.nlm.nih.gov/pubmed/30701236
http://dx.doi.org/10.1128/MRA.01419-18
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