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Safety and efficacy of high‐dose methotrexate for osteosarcoma in adolescents compared with young adults

BACKGROUND: Doxorubicin, cisplatin, and high‐dose methotrexate (HDMTX) are the backbone of pediatric osteosarcoma treatment. However, due to toxicity concerns and the lack of data regarding efficacy in adults, high‐dose methotrexate is rarely used in the adult population. METHODS: This single‐center...

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Detalles Bibliográficos
Autores principales:	Wippel, Brittany, Gundle, Kenneth R., Dang, Theresa, Paxton, Jillian, Bubalo, Joseph, Stork, Linda, Fu, Rongwei, Ryan, Christopher W., Davis, Lara E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Clinical Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346225/ https://www.ncbi.nlm.nih.gov/pubmed/30580500 http://dx.doi.org/10.1002/cam4.1898

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