CCNG1 (Cyclin G1) regulation by mutant‐P53 via induction of Notch3 expression promotes high‐grade serous ovarian cancer (HGSOC) tumorigenesis and progression

TP53 mutation is considerably common in advanced high‐grade serous ovarian cancer (HGSOC) and significantly associated with a poor prognosis. In this study, we investigated the role of Cyclin G1 (CCNG1), a target gene of wild‐type TP53 (P53wt), in HGSOC and the possible regulatory mechanism between...

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Detalles Bibliográficos
Autores principales: Xu, Ying, Zhang, Qing, Miao, Chunying, Dongol, Samina, Li, Yinuo, Jin, Chenjuan, Dong, Ruifeng, Li, Yingwei, Yang, Xingsheng, Kong, Beihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346265/
https://www.ncbi.nlm.nih.gov/pubmed/30565428
http://dx.doi.org/10.1002/cam4.1812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346265/
https://www.ncbi.nlm.nih.gov/pubmed/30565428
http://dx.doi.org/10.1002/cam4.1812

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