Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France

We report a case of atypical cowpox virus infection in France in 2016. The patient sought care for thoracic lesions after injury from the sharp end of a metallic guardrail previously stored in the ground. We isolated a cowpox virus from the lesions and sequenced its whole genome. The patient reporte...

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Detalles Bibliográficos
Autores principales: Andreani, Julien, Arnault, Jean-Philippe, Bou Khalil, Jacques Y., Abrahão, Jônatas, Tomei, Enora, Vial, Emeline, Le Bideau, Marion, Raoult, Didier, La Scola, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Synopsis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346447/
https://www.ncbi.nlm.nih.gov/pubmed/30666929
http://dx.doi.org/10.3201/eid2502.171433
Descripción
Sumario:We report a case of atypical cowpox virus infection in France in 2016. The patient sought care for thoracic lesions after injury from the sharp end of a metallic guardrail previously stored in the ground. We isolated a cowpox virus from the lesions and sequenced its whole genome. The patient reported that he had been previously vaccinated against smallpox. We describe an alternative route of cowpox virus infection and raise questions about the immunological status of smallpox-vaccinated patients for circulating orthopoxviruses.

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