Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France

We report a case of atypical cowpox virus infection in France in 2016. The patient sought care for thoracic lesions after injury from the sharp end of a metallic guardrail previously stored in the ground. We isolated a cowpox virus from the lesions and sequenced its whole genome. The patient reporte...

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Autores principales: Andreani, Julien, Arnault, Jean-Philippe, Bou Khalil, Jacques Y., Abrahão, Jônatas, Tomei, Enora, Vial, Emeline, Le Bideau, Marion, Raoult, Didier, La Scola, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Synopsis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346447/
https://www.ncbi.nlm.nih.gov/pubmed/30666929
http://dx.doi.org/10.3201/eid2502.171433
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author Andreani, Julien
Arnault, Jean-Philippe
Bou Khalil, Jacques Y.
Abrahão, Jônatas
Tomei, Enora
Vial, Emeline
Le Bideau, Marion
Raoult, Didier
La Scola, Bernard
author_facet Andreani, Julien
Arnault, Jean-Philippe
Bou Khalil, Jacques Y.
Abrahão, Jônatas
Tomei, Enora
Vial, Emeline
Le Bideau, Marion
Raoult, Didier
La Scola, Bernard
author_sort Andreani, Julien
collection PubMed
description We report a case of atypical cowpox virus infection in France in 2016. The patient sought care for thoracic lesions after injury from the sharp end of a metallic guardrail previously stored in the ground. We isolated a cowpox virus from the lesions and sequenced its whole genome. The patient reported that he had been previously vaccinated against smallpox. We describe an alternative route of cowpox virus infection and raise questions about the immunological status of smallpox-vaccinated patients for circulating orthopoxviruses.
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spelling pubmed-63464472019-02-01 Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France Andreani, Julien Arnault, Jean-Philippe Bou Khalil, Jacques Y. Abrahão, Jônatas Tomei, Enora Vial, Emeline Le Bideau, Marion Raoult, Didier La Scola, Bernard Emerg Infect Dis Synopsis We report a case of atypical cowpox virus infection in France in 2016. The patient sought care for thoracic lesions after injury from the sharp end of a metallic guardrail previously stored in the ground. We isolated a cowpox virus from the lesions and sequenced its whole genome. The patient reported that he had been previously vaccinated against smallpox. We describe an alternative route of cowpox virus infection and raise questions about the immunological status of smallpox-vaccinated patients for circulating orthopoxviruses. Centers for Disease Control and Prevention 2019-02 /pmc/articles/PMC6346447/ /pubmed/30666929 http://dx.doi.org/10.3201/eid2502.171433 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Synopsis
Andreani, Julien
Arnault, Jean-Philippe
Bou Khalil, Jacques Y.
Abrahão, Jônatas
Tomei, Enora
Vial, Emeline
Le Bideau, Marion
Raoult, Didier
La Scola, Bernard
Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France
title Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France
title_full Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France
title_fullStr Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France
title_full_unstemmed Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France
title_short Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France
title_sort atypical cowpox virus infection in smallpox-vaccinated patient, france
topic Synopsis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346447/
https://www.ncbi.nlm.nih.gov/pubmed/30666929
http://dx.doi.org/10.3201/eid2502.171433
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