Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil

In seroconversion panels obtained from patients from Brazil, diagnostic testing for Zika virus infection was improved by combining multiple antibody isotypes, techniques, and antigens, but sensitivity remained suboptimal. In contrast, chikungunya virus diagnostic testing was unambiguous. Recurrent r...

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Detalles Bibliográficos
Autores principales: Bozza, Fernando A., Moreira-Soto, Andres, Rockstroh, Alexandra, Fischer, Carlo, Nascimento, Alessandra D., Calheiros, Andrea S., Drosten, Christian, Bozza, Patrícia T., Souza, Thiago Moreno L., Ulbert, Sebastian, Drexler, Jan Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346451/
https://www.ncbi.nlm.nih.gov/pubmed/30666934
http://dx.doi.org/10.3201/eid2502.180166
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author Bozza, Fernando A.
Moreira-Soto, Andres
Rockstroh, Alexandra
Fischer, Carlo
Nascimento, Alessandra D.
Calheiros, Andrea S.
Drosten, Christian
Bozza, Patrícia T.
Souza, Thiago Moreno L.
Ulbert, Sebastian
Drexler, Jan Felix
author_facet Bozza, Fernando A.
Moreira-Soto, Andres
Rockstroh, Alexandra
Fischer, Carlo
Nascimento, Alessandra D.
Calheiros, Andrea S.
Drosten, Christian
Bozza, Patrícia T.
Souza, Thiago Moreno L.
Ulbert, Sebastian
Drexler, Jan Felix
author_sort Bozza, Fernando A.
collection PubMed
description In seroconversion panels obtained from patients from Brazil, diagnostic testing for Zika virus infection was improved by combining multiple antibody isotypes, techniques, and antigens, but sensitivity remained suboptimal. In contrast, chikungunya virus diagnostic testing was unambiguous. Recurrent recent arbovirus infections suggested by serologic data and unspecific symptoms highlight the need for exhaustive virologic testing.
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spelling pubmed-63464512019-02-01 Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil Bozza, Fernando A. Moreira-Soto, Andres Rockstroh, Alexandra Fischer, Carlo Nascimento, Alessandra D. Calheiros, Andrea S. Drosten, Christian Bozza, Patrícia T. Souza, Thiago Moreno L. Ulbert, Sebastian Drexler, Jan Felix Emerg Infect Dis Dispatch In seroconversion panels obtained from patients from Brazil, diagnostic testing for Zika virus infection was improved by combining multiple antibody isotypes, techniques, and antigens, but sensitivity remained suboptimal. In contrast, chikungunya virus diagnostic testing was unambiguous. Recurrent recent arbovirus infections suggested by serologic data and unspecific symptoms highlight the need for exhaustive virologic testing. Centers for Disease Control and Prevention 2019-02 /pmc/articles/PMC6346451/ /pubmed/30666934 http://dx.doi.org/10.3201/eid2502.180166 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Bozza, Fernando A.
Moreira-Soto, Andres
Rockstroh, Alexandra
Fischer, Carlo
Nascimento, Alessandra D.
Calheiros, Andrea S.
Drosten, Christian
Bozza, Patrícia T.
Souza, Thiago Moreno L.
Ulbert, Sebastian
Drexler, Jan Felix
Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil
title Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil
title_full Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil
title_fullStr Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil
title_full_unstemmed Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil
title_short Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil
title_sort differential shedding and antibody kinetics of zika and chikungunya viruses, brazil
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346451/
https://www.ncbi.nlm.nih.gov/pubmed/30666934
http://dx.doi.org/10.3201/eid2502.180166
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