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Mannosyltransferase (GPI-14) overexpression protects promastigote and amastigote forms of Leishmania braziliensis against trivalent antimony

BACKGROUND: Glycosylphosphatidylinositol is a surface molecule important for host-parasite interactions. Mannosyltransferase (GPI-14) is an essential enzyme for adding mannose on the glycosylphosphatidyl group. This study attempted to overexpress the GPI-14 gene in Leishmania braziliensis to investi...

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Detalles Bibliográficos
Autores principales:	Ribeiro, Christiana Vargas, Rocha, Bruna Fonte Boa, Moreira, Douglas de Souza, Peruhype-Magalhães, Vanessa, Murta, Silvane Maria Fonseca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346506/ https://www.ncbi.nlm.nih.gov/pubmed/30683152 http://dx.doi.org/10.1186/s13071-019-3305-2

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