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Improved filtering of DNA methylation microarray data by detection p values and its impact on downstream analyses

BACKGROUND: DNA methylation microarrays are popular for epigenome-wide association studies (EWAS), but spurious values complicate downstream analysis and threaten replication. Conventional cut-offs for detection p values for filtering out undetected probes were demonstrated in a single previous stud...

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Detalles Bibliográficos
Autores principales:	Heiss, Jonathan A., Just, Allan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346546/ https://www.ncbi.nlm.nih.gov/pubmed/30678737 http://dx.doi.org/10.1186/s13148-019-0615-3

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