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1α,25(OH)(2)D(3) attenuates IL-6 and IL-1β-mediated inflammatory responses in macrophage conditioned medium-stimulated human white preadipocytes by modulating p44/42 MAPK and NF-κB signaling pathways

BACKGROUND: Metabolic syndrome is characterized by macrophage infiltration and inflammatory responses—metaflammation in adipose tissue. IL-6 and IL-1β could mediate the inflammatory responses in macrophage stimulated-preadipocytes by modulating MAPK and NF-κB pathways. To test this hypothesis we use...

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Detalles Bibliográficos
Autores principales:	Zhu, Jingjing, Bing, Chen, Wilding, John P. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346557/ https://www.ncbi.nlm.nih.gov/pubmed/30697360 http://dx.doi.org/10.1186/s13098-019-0405-2

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