Leptin-deficient mice have altered three-dimensional growth plate histomorphometry

BACKGROUND: Leptin is an adipokine that regulates energy homeostasis and is also needed for normal bone growth and maintenance. Mutation in the lep gene, which characterizes the ob/ob mouse model, results in the development of obesity and type 2 diabetes mellitus, as well as reduced limb bone length...

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Detalles Bibliográficos
Autores principales: Hung, Jun, Al-Nakkash, Layla, Broderick, Tom L., Castro, Monica, Plochocki, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346570/
https://www.ncbi.nlm.nih.gov/pubmed/30697359
http://dx.doi.org/10.1186/s13098-019-0402-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346570/
https://www.ncbi.nlm.nih.gov/pubmed/30697359
http://dx.doi.org/10.1186/s13098-019-0402-5

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