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Transcriptome-guided target identification of the TetR-like regulator SACE_5754 and engineered overproduction of erythromycin in Saccharopolyspora erythraea

BACKGROUND: Erythromycin A (Er-A) produced by the actinomycete Saccharopolyspora erythraea is an important antibiotic extensively used in human medicine. Dissecting of transcriptional regulators and their target genes associated with erythromycin biosynthesis is crucial to obtain erythromycin overpr...

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Detalles Bibliográficos
Autores principales:	Wu, Hang, Chu, Zuling, Zhang, Wanxiang, Zhang, Chi, Ni, Jingshu, Fang, Heshi, Chen, Yuhong, Wang, Yansheng, Zhang, Lixin, Zhang, Buchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346578/ https://www.ncbi.nlm.nih.gov/pubmed/30697347 http://dx.doi.org/10.1186/s13036-018-0135-2

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