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A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions

Sarcoidosis is a systemic disorder that most commonly affects the lungs. Bone involvement is rare, and spinal involvement is even more rare. The presence of focal lesions of the vertebrae is highly suspicious of advanced malignancy. However, malignant metastatic spread to the spine involves the vert...

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Detalles Bibliográficos
Autores principales: Bel-ange, Anat, Tal, Sigal, Rapoport, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346829/
https://www.ncbi.nlm.nih.gov/pubmed/30756058
http://dx.doi.org/10.12890/2018_00907
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author Bel-ange, Anat
Tal, Sigal
Rapoport, Micha
author_facet Bel-ange, Anat
Tal, Sigal
Rapoport, Micha
author_sort Bel-ange, Anat
collection PubMed
description Sarcoidosis is a systemic disorder that most commonly affects the lungs. Bone involvement is rare, and spinal involvement is even more rare. The presence of focal lesions of the vertebrae is highly suspicious of advanced malignancy. However, malignant metastatic spread to the spine involves the vertebral cortex rather than the bone marrow itself, a distinction that is often missed and therefore misleading. We describe here a middle-aged woman with multiple focal oedematous lesions of the bone marrow suspected of being advanced malignancy but finally diagnosed as a rare case of spinal sarcoidosis. LEARNING POINTS: This article describes a rare case of vertebral sarcoidosis. It emphasizes the often-missed distinction between bone marrow and cortical lesions in the diagnostic work-up of focal spinal lesions. It also underscores the combined use of MRI together with FDG/PET-CT in elucidating the nature of lesions confined to the bone marrow.
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spelling pubmed-63468292019-02-12 A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions Bel-ange, Anat Tal, Sigal Rapoport, Micha Eur J Case Rep Intern Med Articles Sarcoidosis is a systemic disorder that most commonly affects the lungs. Bone involvement is rare, and spinal involvement is even more rare. The presence of focal lesions of the vertebrae is highly suspicious of advanced malignancy. However, malignant metastatic spread to the spine involves the vertebral cortex rather than the bone marrow itself, a distinction that is often missed and therefore misleading. We describe here a middle-aged woman with multiple focal oedematous lesions of the bone marrow suspected of being advanced malignancy but finally diagnosed as a rare case of spinal sarcoidosis. LEARNING POINTS: This article describes a rare case of vertebral sarcoidosis. It emphasizes the often-missed distinction between bone marrow and cortical lesions in the diagnostic work-up of focal spinal lesions. It also underscores the combined use of MRI together with FDG/PET-CT in elucidating the nature of lesions confined to the bone marrow. SMC Media Srl 2018-08-28 /pmc/articles/PMC6346829/ /pubmed/30756058 http://dx.doi.org/10.12890/2018_00907 Text en © EFIM 2018 This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Articles
Bel-ange, Anat
Tal, Sigal
Rapoport, Micha
A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions
title A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions
title_full A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions
title_fullStr A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions
title_full_unstemmed A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions
title_short A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions
title_sort rare case of spinal sarcoidosis presenting as multiple bone marrow oedematous lesions
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346829/
https://www.ncbi.nlm.nih.gov/pubmed/30756058
http://dx.doi.org/10.12890/2018_00907
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