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A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions
Sarcoidosis is a systemic disorder that most commonly affects the lungs. Bone involvement is rare, and spinal involvement is even more rare. The presence of focal lesions of the vertebrae is highly suspicious of advanced malignancy. However, malignant metastatic spread to the spine involves the vert...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SMC Media Srl
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346829/ https://www.ncbi.nlm.nih.gov/pubmed/30756058 http://dx.doi.org/10.12890/2018_00907 |
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author | Bel-ange, Anat Tal, Sigal Rapoport, Micha |
author_facet | Bel-ange, Anat Tal, Sigal Rapoport, Micha |
author_sort | Bel-ange, Anat |
collection | PubMed |
description | Sarcoidosis is a systemic disorder that most commonly affects the lungs. Bone involvement is rare, and spinal involvement is even more rare. The presence of focal lesions of the vertebrae is highly suspicious of advanced malignancy. However, malignant metastatic spread to the spine involves the vertebral cortex rather than the bone marrow itself, a distinction that is often missed and therefore misleading. We describe here a middle-aged woman with multiple focal oedematous lesions of the bone marrow suspected of being advanced malignancy but finally diagnosed as a rare case of spinal sarcoidosis. LEARNING POINTS: This article describes a rare case of vertebral sarcoidosis. It emphasizes the often-missed distinction between bone marrow and cortical lesions in the diagnostic work-up of focal spinal lesions. It also underscores the combined use of MRI together with FDG/PET-CT in elucidating the nature of lesions confined to the bone marrow. |
format | Online Article Text |
id | pubmed-6346829 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | SMC Media Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-63468292019-02-12 A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions Bel-ange, Anat Tal, Sigal Rapoport, Micha Eur J Case Rep Intern Med Articles Sarcoidosis is a systemic disorder that most commonly affects the lungs. Bone involvement is rare, and spinal involvement is even more rare. The presence of focal lesions of the vertebrae is highly suspicious of advanced malignancy. However, malignant metastatic spread to the spine involves the vertebral cortex rather than the bone marrow itself, a distinction that is often missed and therefore misleading. We describe here a middle-aged woman with multiple focal oedematous lesions of the bone marrow suspected of being advanced malignancy but finally diagnosed as a rare case of spinal sarcoidosis. LEARNING POINTS: This article describes a rare case of vertebral sarcoidosis. It emphasizes the often-missed distinction between bone marrow and cortical lesions in the diagnostic work-up of focal spinal lesions. It also underscores the combined use of MRI together with FDG/PET-CT in elucidating the nature of lesions confined to the bone marrow. SMC Media Srl 2018-08-28 /pmc/articles/PMC6346829/ /pubmed/30756058 http://dx.doi.org/10.12890/2018_00907 Text en © EFIM 2018 This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Articles Bel-ange, Anat Tal, Sigal Rapoport, Micha A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions |
title | A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions |
title_full | A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions |
title_fullStr | A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions |
title_full_unstemmed | A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions |
title_short | A Rare Case of Spinal Sarcoidosis Presenting as Multiple Bone Marrow Oedematous Lesions |
title_sort | rare case of spinal sarcoidosis presenting as multiple bone marrow oedematous lesions |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346829/ https://www.ncbi.nlm.nih.gov/pubmed/30756058 http://dx.doi.org/10.12890/2018_00907 |
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