Purpura is Not Always Caused by the Anticoagulant

Pigmented purpuric dermatosis is a chronic benign skin disorder of unknown aetiology. Although there are several other potential cofactors, drugs are the most frequent cause. This paper describes the case of a 71-year-old woman who was admitted in the emergency department with skin lesions on the lower extremities, characteristics of Schamberg’s disease. After a medical study and treatment, it was concluded that the lesions were caused by amlodipine administration. To the authors’ knowledge, only one previous case describing an association between this disease and amlodipine administration has been reported in the medical literature. LEARNING POINTS: Schamberg’s disease is the most common form of pigmented purpuric dermatosis. The condition can be caused by amlodipine administration. This is a rare but benign skin disorder.