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A Challenging Diagnosis of Leg Ulcer

Ischaemic ulcers of the lower limb can have several aethiopathological mechanisms. For instance, the uncommon Martorell hypertensive leg ulcer is an infrequent complication of long-term uncontrolled arterial hypertension and is largely ignored and underdiagnosed. The typical ulcer is on the lower le...

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Autores principales: Serpa, Maria João, Franco, Susana, Repolho, Diana, Araújo, Isabel, Mateus, Sofia, Baptista, António Martins, Araújo, José Lomelino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346891/
https://www.ncbi.nlm.nih.gov/pubmed/30755982
http://dx.doi.org/10.12890/2018_000952
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author Serpa, Maria João
Franco, Susana
Repolho, Diana
Araújo, Isabel
Mateus, Sofia
Baptista, António Martins
Araújo, José Lomelino
author_facet Serpa, Maria João
Franco, Susana
Repolho, Diana
Araújo, Isabel
Mateus, Sofia
Baptista, António Martins
Araújo, José Lomelino
author_sort Serpa, Maria João
collection PubMed
description Ischaemic ulcers of the lower limb can have several aethiopathological mechanisms. For instance, the uncommon Martorell hypertensive leg ulcer is an infrequent complication of long-term uncontrolled arterial hypertension and is largely ignored and underdiagnosed. The typical ulcer is on the lower leg, is extremely painful and presents in female patients over 60 years of age with cardiovascular risk factors, mainly severe arterial hypertension. The diagnosis is histological, with obliteration of the arterioles by arteriolosclerosis. In these cases, antihypertensive medication is the standard treatment. We describe the case of an African-American female patient with long-term hypertension who presented with a very painful leg ulcer. The diagnosis was complicated by the coexistence of more common causes of ulcer. Despite analgesic medicines, pain relief was only obtained with control of hypertension. A definite diagnosis was made following biopsy. In describing this diagnosis of an ischaemic leg ulcer, we highlight the need to consider the skin as a target organ of arterial hypertension. LEARNING POINTS: Martorell hypertensive leg ulcer is an underdiagnosed cutaneous lesion arising from long-term uncontrolled hypertension. The diagnosis is confirmed by histopathology. Standard treatment is adequate control of blood pressure.
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spelling pubmed-63468912019-02-12 A Challenging Diagnosis of Leg Ulcer Serpa, Maria João Franco, Susana Repolho, Diana Araújo, Isabel Mateus, Sofia Baptista, António Martins Araújo, José Lomelino Eur J Case Rep Intern Med Articles Ischaemic ulcers of the lower limb can have several aethiopathological mechanisms. For instance, the uncommon Martorell hypertensive leg ulcer is an infrequent complication of long-term uncontrolled arterial hypertension and is largely ignored and underdiagnosed. The typical ulcer is on the lower leg, is extremely painful and presents in female patients over 60 years of age with cardiovascular risk factors, mainly severe arterial hypertension. The diagnosis is histological, with obliteration of the arterioles by arteriolosclerosis. In these cases, antihypertensive medication is the standard treatment. We describe the case of an African-American female patient with long-term hypertension who presented with a very painful leg ulcer. The diagnosis was complicated by the coexistence of more common causes of ulcer. Despite analgesic medicines, pain relief was only obtained with control of hypertension. A definite diagnosis was made following biopsy. In describing this diagnosis of an ischaemic leg ulcer, we highlight the need to consider the skin as a target organ of arterial hypertension. LEARNING POINTS: Martorell hypertensive leg ulcer is an underdiagnosed cutaneous lesion arising from long-term uncontrolled hypertension. The diagnosis is confirmed by histopathology. Standard treatment is adequate control of blood pressure. SMC Media Srl 2018-10-24 /pmc/articles/PMC6346891/ /pubmed/30755982 http://dx.doi.org/10.12890/2018_000952 Text en © EFIM 2018 This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Articles
Serpa, Maria João
Franco, Susana
Repolho, Diana
Araújo, Isabel
Mateus, Sofia
Baptista, António Martins
Araújo, José Lomelino
A Challenging Diagnosis of Leg Ulcer
title A Challenging Diagnosis of Leg Ulcer
title_full A Challenging Diagnosis of Leg Ulcer
title_fullStr A Challenging Diagnosis of Leg Ulcer
title_full_unstemmed A Challenging Diagnosis of Leg Ulcer
title_short A Challenging Diagnosis of Leg Ulcer
title_sort challenging diagnosis of leg ulcer
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346891/
https://www.ncbi.nlm.nih.gov/pubmed/30755982
http://dx.doi.org/10.12890/2018_000952
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