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Hypoglyceamia in a Patient with a Solitary Fibrous Tumour

OBJECTIVE: To illustrate an unusual mechanism causing hypoglycaemia. MATERIAL AND METHODS: A 76-year-old man presented with episodes of agitation and confusion and was resuscitated with oral glucose gel when found to be hypoglycaemic. RESULTS: A CT scan for an abdominal mass confirmed a solitary fib...

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Detalles Bibliográficos
Autores principales: Okpe, Andrew, Ramsay, Kerri, Fernando, Isuru P, Mudenha, Emily, Fernando, Devaka JS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346903/
https://www.ncbi.nlm.nih.gov/pubmed/30755862
http://dx.doi.org/10.12890/2016_000353
Descripción
Sumario:OBJECTIVE: To illustrate an unusual mechanism causing hypoglycaemia. MATERIAL AND METHODS: A 76-year-old man presented with episodes of agitation and confusion and was resuscitated with oral glucose gel when found to be hypoglycaemic. RESULTS: A CT scan for an abdominal mass confirmed a solitary fibrous tumour (SFT). The sarcoma multidisciplinary team suggested conservative management. The patient’s episodic hypoglycaemia was managed with diet modification including corn-based starch, scheduled snacks and dexamethasone. Glucose levels were within normal range at discharge from hospital. The patient was referred to the palliative care team for follow-up. CONCLUSION: SFTs causing non-islet cell tumour hypoglycaemia are difficult to treat. LEARNING POINTS: To be aware of rarer causes of hypoglycaemia and to consider unusual causes in acute presentations of hypoglycaemia, especially in patients who do not have diabetes. This case illustrates the importance of a thorough general physical and systemic examination, as identifying the abdominal mass is essential to the early diagnosis of this rare condition. Solitary fibrous tumours causing non-islet cell tumour hypoglycaemia are difficult to treat, and even when surgical resections are applicable, recurrence rates are high.