Self-antigen MASH2 combined with the AS15 immunostimulant induces tumor protection in colorectal cancer mouse models

Human achaete scute homolog 2 (HASH2) and its murine ortholog MASH2 are potential targets for colorectal cancer immunotherapy. We assessed immunogenicity and antitumor potential of recombinant MASH2 protein combined with AS15 immunostimulant (recMASH2+AS15) in CB6F1 and Apc(+/Min-FCCC) mice. CB6F1 m...

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Detalles Bibliográficos
Autores principales: Rioux, Clément R., Clapper, Margie L., Cooper, Harry S., Michaud, Jean, St Amant, Natalie, Koohsari, Hossein, Workman, Laura, Kaunga, Esther, Hensley, Harvey, Pilorget, Anthony, Gerard, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347180/
https://www.ncbi.nlm.nih.gov/pubmed/30682058
http://dx.doi.org/10.1371/journal.pone.0210261

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