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Potential off-target effects of beta-blockers on gut hormone receptors: In silico study including GUT-DOCK—A web service for small-molecule docking
The prolonged use of many currently available drugs results in the severe side effect of the disruption of glucose metabolism leading to type 2 diabetes mellitus (T2DM. Gut hormone receptors including glucagon receptor (GCGR) and the incretin hormone receptors: glucagon-like peptide 1 receptor (GLP1...
Autores principales: | Pasznik, Pawel, Rutkowska, Ewelina, Niewieczerzal, Szymon, Cielecka-Piontek, Judyta, Latek, Dorota |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347188/ https://www.ncbi.nlm.nih.gov/pubmed/30682072 http://dx.doi.org/10.1371/journal.pone.0210705 |
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