MALDI imaging mass spectrometry revealed atropine distribution in the ocular tissues and its transit from anterior to posterior regions in the whole-eye of rabbit after topical administration

It is essential to elucidate drug distribution in the ocular tissues and drug transit in the eye for ophthalmic pharmaceutical manufacturers. Atropine is a reversible muscarinic receptor used to treat various diseases. However, its distribution in ocular tissues is still incompletely understood. Mat...

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Detalles Bibliográficos
Autores principales: Mori, Naoto, Mochizuki, Takaharu, Yamazaki, Fumiyoshi, Takei, Shiro, Mano, Hidetoshi, Matsugi, Takeshi, Setou, Mitsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347209/
https://www.ncbi.nlm.nih.gov/pubmed/30682156
http://dx.doi.org/10.1371/journal.pone.0211376

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