Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma

Corticosteroid-binding globulin (CBG) transports glucocorticoids in blood and is a serine protease inhibitor family member. Human CBG has a reactive center loop (RCL) which, when cleaved by neutrophil elastase (NE), disrupts its steroid-binding activity. Measurements of CBG levels are typically base...

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Detalles Bibliográficos
Autores principales: Hill, Lesley A, Vassiliadi, Dimitra A, Dimopoulou, Ioanna, Anderson, Anna J, Boyle, Luke D, Kilgour, Alixe H M, Stimson, Roland H, Machado, Yoan, Overall, Christopher M, Walker, Brian R, Lewis, John G, Hammond, Geoffrey L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347282/
https://www.ncbi.nlm.nih.gov/pubmed/30452386
http://dx.doi.org/10.1530/JOE-18-0479

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