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Cyclodextrins as multifunctional excipients: Influence of inclusion into β-cyclodextrin on physicochemical and biological properties of tebipenem pivoxil

A novel approach for drug design based on the oral carbapenem analog tebipenem pivoxil (TP) has been proposed. The formation of the tebipenem pivoxil-β-cyclodextrin (TP-β-CD) complex resulted in changes concerning physicochemical properties of TP, which is significant for planning the development of...

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Detalles Bibliográficos
Autores principales:	Paczkowska, Magdalena, Szymanowska-Powałowska, Daria, Mizera, Mikołaj, Siąkowska, Dominika, Błaszczak, Wioletta, Piotrowska-Kempisty, Hanna, Cielecka-Piontek, Judyta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347292/ https://www.ncbi.nlm.nih.gov/pubmed/30682086 http://dx.doi.org/10.1371/journal.pone.0210694

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