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VPAC1 receptors play a dominant role in PACAP-induced vasorelaxation in female mice

BACKGROUND: PACAP and VIP are closely related neuropeptides with wide distribution and potent effect in the vasculature. We previously reported vasomotor activity in peripheral vasculature of male wild type (WT) and PACAP-deficient (KO) mice. However, female vascular responses are still unexplored....

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Detalles Bibliográficos
Autores principales: Ivic, Ivan, Balasko, Marta, Fulop, Balazs D., Hashimoto, Hitoshi, Toth, Gabor, Tamas, Andrea, Juhasz, Tamas, Koller, Akos, Reglodi, Dora, Solymár, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347420/
https://www.ncbi.nlm.nih.gov/pubmed/30682157
http://dx.doi.org/10.1371/journal.pone.0211433