Heme detoxification by heme oxygenase-1 reinstates proliferative and immune balances upon genotoxic tissue injury

Phenotypic changes of myeloid cells are critical to the regulation of premature aging, development of cancer, and responses to infection. Heme metabolism has a fundamental role in the regulation of myeloid cell function and activity. Here, we show that deletion of heme oxygenase-1 (HO-1), an enzyme...

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Detalles Bibliográficos
Autores principales: Hedblom, Andreas, Hejazi, Seyed M., Canesin, Giacomo, Choudhury, Reeham, Hanafy, Khalid A., Csizmadia, Eva, Persson, Jenny L., Wegiel, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347604/
https://www.ncbi.nlm.nih.gov/pubmed/30683864
http://dx.doi.org/10.1038/s41419-019-1342-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347604/
https://www.ncbi.nlm.nih.gov/pubmed/30683864
http://dx.doi.org/10.1038/s41419-019-1342-6

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