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Heme detoxification by heme oxygenase-1 reinstates proliferative and immune balances upon genotoxic tissue injury
Phenotypic changes of myeloid cells are critical to the regulation of premature aging, development of cancer, and responses to infection. Heme metabolism has a fundamental role in the regulation of myeloid cell function and activity. Here, we show that deletion of heme oxygenase-1 (HO-1), an enzyme...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347604/ https://www.ncbi.nlm.nih.gov/pubmed/30683864 http://dx.doi.org/10.1038/s41419-019-1342-6 |