Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport

The intracellular ciliogenesis pathway requires membrane trafficking, fusion, and reorganization. Here, we demonstrate in human cells and zebrafish that the F-BAR domain containing proteins PACSIN1 and -2 play an essential role in ciliogenesis, similar to their binding partner and membrane reorganiz...

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Detalles Bibliográficos
Autores principales: Insinna, Christine, Lu, Quanlong, Teixeira, Isabella, Harned, Adam, Semler, Elizabeth M., Stauffer, Jim, Magidson, Valentin, Tiwari, Ajit, Kenworthy, Anne K., Narayan, Kedar, Westlake, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347608/
https://www.ncbi.nlm.nih.gov/pubmed/30683896
http://dx.doi.org/10.1038/s41467-018-08192-9

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