Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella

Aberrant sperm flagella impair sperm motility and cause male infertility, yet the genes which have been identified in multiple morphological abnormalities of the flagella (MMAF) can only explain the pathogenic mechanisms of MMAF in a small number of cases. Here, we identify and functionally characte...

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Detalles Bibliográficos
Autores principales: Shen, Ying, Zhang, Feng, Li, Fuping, Jiang, Xiaohui, Yang, Yihong, Li, Xiaoliang, Li, Weiyu, Wang, Xiang, Cheng, Juan, Liu, Mohan, Zhang, Xueguang, Yuan, Guiping, Pei, Xue, Cai, Kailai, Hu, Fengyun, Sun, Jianfeng, Yan, Lanzhen, Tang, Li, Jiang, Chuan, Tu, Wenling, Xu, Jinyan, Wu, Haojuan, Kong, Weiqi, Li, Shuying, Wang, Ke, Sheng, Kai, Zhao, Xudong, Yue, Huanxun, Yang, Xiaoyu, Xu, Wenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347614/
https://www.ncbi.nlm.nih.gov/pubmed/30683861
http://dx.doi.org/10.1038/s41467-018-08182-x

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