Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation

Group 2 innate lymphoid cells (ILC2s) have tissue-resident competence and contribute to the pathogenesis of allergic diseases. However, the mechanisms regulating prolonged ILC2-mediated T(H)2 cytokine production under chronic inflammatory conditions are unclear. Here we show that, at homeostasis, Ru...

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Detalles Bibliográficos
Autores principales: Miyamoto, Chizuko, Kojo, Satoshi, Yamashita, Motoi, Moro, Kazuyo, Lacaud, Georges, Shiroguchi, Katsuyuki, Taniuchi, Ichiro, Ebihara, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347616/
https://www.ncbi.nlm.nih.gov/pubmed/30683858
http://dx.doi.org/10.1038/s41467-019-08365-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347616/
https://www.ncbi.nlm.nih.gov/pubmed/30683858
http://dx.doi.org/10.1038/s41467-019-08365-0

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