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Action and mechanism of the colistin resistance enzyme MCR-4

Colistin is the last-resort antibiotic against lethal infections with multidrug-resistant bacterial pathogens. A rainbow coalition of mobile colistin resistance (mcr) genes raises global health concerns. Here, we describe the action and mechanism of colistin resistance imparted by MCR-4, a recently-...

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Detalles Bibliográficos
Autores principales: Zhang, Huimin, Hou, Mengyun, Xu, Yongchang, Srinivas, Swaminath, Huang, Man, Liu, Lizhang, Feng, Youjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347640/
https://www.ncbi.nlm.nih.gov/pubmed/30701201
http://dx.doi.org/10.1038/s42003-018-0278-1