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Anthrax toxin requires ZDHHC5-mediated palmitoylation of its surface-processing host enzymes
The protein acyl transferase ZDHHC5 was recently proposed to regulate trafficking in the endocytic pathway. Therefore, we explored the function of this enzyme in controlling the action of bacterial toxins. We found that ZDHHC5 activity is required for two very different toxins: the anthrax lethal to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347675/ https://www.ncbi.nlm.nih.gov/pubmed/30610172 http://dx.doi.org/10.1073/pnas.1812588116 |