Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody

Breast cancers enduring treatment with chemotherapy may be enriched for cancer stem cells or tumor-initiating cells, which have an enhanced capacity for self-renewal, tumor initiation, and/or metastasis. Breast cancer cells that express the type I tyrosine kinaselike orphan receptor ROR1 also may ha...

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Detalles Bibliográficos
Autores principales: Zhang, Suping, Zhang, Han, Ghia, Emanuela M., Huang, Jiajia, Wu, Liufeng, Zhang, Jianchao, Lam, Sharon, Lei, Yang, He, Jinsong, Cui, Bing, Widhopf, George F., Yu, Jian, Schwab, Richard, Messer, Karen, Jiang, Wenqi, Parker, Barbara A., Carson, Dennis A., Kipps, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347692/
https://www.ncbi.nlm.nih.gov/pubmed/30622177
http://dx.doi.org/10.1073/pnas.1816262116

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