Flow Cytometry of CD64, HLA-DR, CD25, and TLRs for Diagnosis and Prognosis of Sepsis in Critically Ill Patients Admitted to the Intensive Care Unit: A Review Article

Sepsis is an important health problem with a high burden on health systems. Finding new aspects of immune system function in sepsis showed a new role for flow cytometry in the diagnosis of sepsis. We made a review on the role of CD64, HLA-DR, CD25, and TLRs as more useful flow cytometric tools in di...

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Detalles Bibliográficos
Autores principales: Mahmoodpoor, Ata, Paknezhad, Seyedpouya, Shadvar, Kamran, Hamishehkar, Hadi, Movassaghpour, Ali Akbar, Sanaie, Sarvin, Ghamari, Ali Akbar, Soleimanpour, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347736/
https://www.ncbi.nlm.nih.gov/pubmed/30719416
http://dx.doi.org/10.5812/aapm.83128
Descripción
Sumario:Sepsis is an important health problem with a high burden on health systems. Finding new aspects of immune system function in sepsis showed a new role for flow cytometry in the diagnosis of sepsis. We made a review on the role of CD64, HLA-DR, CD25, and TLRs as more useful flow cytometric tools in diagnosing sepsis, both in adults, and neonates. According to our results, we concluded that for diagnosis and treatment of the septic, flow cytometry can play an important role so that it can be used as a novel method in individualized treatment of septic patients based on their immune system situation.

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