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Epigenetic inactivation of HOXD10 is associated with human colon cancer via inhibiting the RHOC/AKT/MAPK signaling pathway

BACKGROUND: To examine the influence of HOXD10 on the metabolism and growth of colon carcinoma cells by suppressing the RHOC/AKT/MAPK pathway. METHODS: Thirty-seven paired colon cancer and its adjacent samples from The Cancer Genome Atlas (TCGA) were analyzed. Chip Analysis Methylation Pipeline (ChA...

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Detalles Bibliográficos
Autores principales:	Yuan, Yu-hong, Wang, Han-yu, Lai, Yu, Zhong, Wa, Liang, Wei-ling, Yan, Fu-de, Yu, Zhong, Chen, Jun-kai, Lin, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347846/ https://www.ncbi.nlm.nih.gov/pubmed/30683109 http://dx.doi.org/10.1186/s12964-018-0316-0

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