Cargando…

Neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study

OBJECTIVES: To describe the acceptability, safety and effectiveness of neuromuscular electrical stimulation (NMES) in infants and young children with neurological impairment (NI) who have severe dysphagia. DESIGN: A prospective pilot study using a before and after study design. SETTING: The Hospital...

Descripción completa

Detalles Bibliográficos
Autores principales: Marcus, Sherna, Friedman, Jeremy N, Lacombe-Duncan, Ashley, Mahant, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347906/
https://www.ncbi.nlm.nih.gov/pubmed/30740545
http://dx.doi.org/10.1136/bmjpo-2018-000382
_version_ 1783390016375881728
author Marcus, Sherna
Friedman, Jeremy N
Lacombe-Duncan, Ashley
Mahant, Sanjay
author_facet Marcus, Sherna
Friedman, Jeremy N
Lacombe-Duncan, Ashley
Mahant, Sanjay
author_sort Marcus, Sherna
collection PubMed
description OBJECTIVES: To describe the acceptability, safety and effectiveness of neuromuscular electrical stimulation (NMES) in infants and young children with neurological impairment (NI) who have severe dysphagia. DESIGN: A prospective pilot study using a before and after study design. SETTING: The Hospital for Sick Children, Toronto, Canada. PATIENTS: Ten infants and young children (0–24 months) with NI and severe dysphagia on videofluoroscopic swallow study (VFSS) who were referred to an occupational therapist (OT). Those with neurodegenerative conditions were excluded. INTERVENTION: NMES treatments lasting 20–45 min twice weekly for the duration of 2–4 months. The NMES was administered during feeding therapy sessions by a trained OT. MAIN OUTCOME MEASURES: Improvement in swallowing function as measured by VFSS and the need for tube feeding, adverse events and parental acceptability. RESULTS: Seven of 10 enrolled subjects (median age, 8.9 months) completed biweekly NMES treatments (median number of treatments per subject, 18). All of the seven (100%) subjects who completed treatment showed an improvement in swallow function on VFSS. Of the five patients who were not safe to orally feed on any consistency of liquid or puree at baseline, three established full oral feeding and two established partial oral feeding. At baseline, 5/7 children were completely fed by tube versus 0/7 at the end of treatment. No adverse events occurred other than mild skin irritation at the site of electrode placement. Five of seven caregivers felt that feeding was improved and were satisfied with the intervention. CONCLUSIONS: Our prospective pilot study of NMES in seven neurologically impaired infants and young children with severe dysphagia suggests that NMES is safe, acceptable to parents and has potential efficacy. Trials are needed to determine if any treatment benefit exists. TRIAL REGISTRATION: ClinicalTrials.gov NCT01723358.
format Online
Article
Text
id pubmed-6347906
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-63479062019-02-08 Neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study Marcus, Sherna Friedman, Jeremy N Lacombe-Duncan, Ashley Mahant, Sanjay BMJ Paediatr Open Neurodisability OBJECTIVES: To describe the acceptability, safety and effectiveness of neuromuscular electrical stimulation (NMES) in infants and young children with neurological impairment (NI) who have severe dysphagia. DESIGN: A prospective pilot study using a before and after study design. SETTING: The Hospital for Sick Children, Toronto, Canada. PATIENTS: Ten infants and young children (0–24 months) with NI and severe dysphagia on videofluoroscopic swallow study (VFSS) who were referred to an occupational therapist (OT). Those with neurodegenerative conditions were excluded. INTERVENTION: NMES treatments lasting 20–45 min twice weekly for the duration of 2–4 months. The NMES was administered during feeding therapy sessions by a trained OT. MAIN OUTCOME MEASURES: Improvement in swallowing function as measured by VFSS and the need for tube feeding, adverse events and parental acceptability. RESULTS: Seven of 10 enrolled subjects (median age, 8.9 months) completed biweekly NMES treatments (median number of treatments per subject, 18). All of the seven (100%) subjects who completed treatment showed an improvement in swallow function on VFSS. Of the five patients who were not safe to orally feed on any consistency of liquid or puree at baseline, three established full oral feeding and two established partial oral feeding. At baseline, 5/7 children were completely fed by tube versus 0/7 at the end of treatment. No adverse events occurred other than mild skin irritation at the site of electrode placement. Five of seven caregivers felt that feeding was improved and were satisfied with the intervention. CONCLUSIONS: Our prospective pilot study of NMES in seven neurologically impaired infants and young children with severe dysphagia suggests that NMES is safe, acceptable to parents and has potential efficacy. Trials are needed to determine if any treatment benefit exists. TRIAL REGISTRATION: ClinicalTrials.gov NCT01723358. BMJ Publishing Group 2019-01-23 /pmc/articles/PMC6347906/ /pubmed/30740545 http://dx.doi.org/10.1136/bmjpo-2018-000382 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Neurodisability
Marcus, Sherna
Friedman, Jeremy N
Lacombe-Duncan, Ashley
Mahant, Sanjay
Neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study
title Neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study
title_full Neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study
title_fullStr Neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study
title_full_unstemmed Neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study
title_short Neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study
title_sort neuromuscular electrical stimulation for treatment of dysphagia in infants and young children with neurological impairment: a prospective pilot study
topic Neurodisability
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347906/
https://www.ncbi.nlm.nih.gov/pubmed/30740545
http://dx.doi.org/10.1136/bmjpo-2018-000382
work_keys_str_mv AT marcussherna neuromuscularelectricalstimulationfortreatmentofdysphagiaininfantsandyoungchildrenwithneurologicalimpairmentaprospectivepilotstudy
AT friedmanjeremyn neuromuscularelectricalstimulationfortreatmentofdysphagiaininfantsandyoungchildrenwithneurologicalimpairmentaprospectivepilotstudy
AT lacombeduncanashley neuromuscularelectricalstimulationfortreatmentofdysphagiaininfantsandyoungchildrenwithneurologicalimpairmentaprospectivepilotstudy
AT mahantsanjay neuromuscularelectricalstimulationfortreatmentofdysphagiaininfantsandyoungchildrenwithneurologicalimpairmentaprospectivepilotstudy