GenoDup Pipeline: a tool to detect genome duplication using the dS-based method

Understanding whole genome duplication (WGD), or polyploidy, is fundamental to investigating the origin and diversification of organisms in evolutionary biology. The wealth of genomic data generated by next generation sequencing (NGS) has resulted in an urgent need for handy and accurate tools to de...

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Detalles Bibliográficos
Autor principal: Mao, Yafei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347962/
https://www.ncbi.nlm.nih.gov/pubmed/30697488
http://dx.doi.org/10.7717/peerj.6303
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author Mao, Yafei
author_facet Mao, Yafei
author_sort Mao, Yafei
collection PubMed
description Understanding whole genome duplication (WGD), or polyploidy, is fundamental to investigating the origin and diversification of organisms in evolutionary biology. The wealth of genomic data generated by next generation sequencing (NGS) has resulted in an urgent need for handy and accurate tools to detect WGD. Here, I present a useful and user-friendly pipeline called GenoDup for inferring WGD using the dS-based method. I have successfully applied GenoDup to identify WGD in empirical data from both plants and animals. The GenoDup Pipeline provides a reliable and useful tool to infer WGD from NGS data.
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spelling pubmed-63479622019-01-29 GenoDup Pipeline: a tool to detect genome duplication using the dS-based method Mao, Yafei PeerJ Bioinformatics Understanding whole genome duplication (WGD), or polyploidy, is fundamental to investigating the origin and diversification of organisms in evolutionary biology. The wealth of genomic data generated by next generation sequencing (NGS) has resulted in an urgent need for handy and accurate tools to detect WGD. Here, I present a useful and user-friendly pipeline called GenoDup for inferring WGD using the dS-based method. I have successfully applied GenoDup to identify WGD in empirical data from both plants and animals. The GenoDup Pipeline provides a reliable and useful tool to infer WGD from NGS data. PeerJ Inc. 2019-01-23 /pmc/articles/PMC6347962/ /pubmed/30697488 http://dx.doi.org/10.7717/peerj.6303 Text en ©2019 Mao http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Bioinformatics
Mao, Yafei
GenoDup Pipeline: a tool to detect genome duplication using the dS-based method
title GenoDup Pipeline: a tool to detect genome duplication using the dS-based method
title_full GenoDup Pipeline: a tool to detect genome duplication using the dS-based method
title_fullStr GenoDup Pipeline: a tool to detect genome duplication using the dS-based method
title_full_unstemmed GenoDup Pipeline: a tool to detect genome duplication using the dS-based method
title_short GenoDup Pipeline: a tool to detect genome duplication using the dS-based method
title_sort genodup pipeline: a tool to detect genome duplication using the ds-based method
topic Bioinformatics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347962/
https://www.ncbi.nlm.nih.gov/pubmed/30697488
http://dx.doi.org/10.7717/peerj.6303
work_keys_str_mv AT maoyafei genoduppipelineatooltodetectgenomeduplicationusingthedsbasedmethod

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