Gene expression variability across cells and species shapes innate immunity

As the first line of defence against pathogens, cells mount an innate immune response, which is highly variable from cell to cell. The response must be potent yet carefully controlled to avoid self-damage. How these constraints have shaped the evolution of innate immunity remains poorly understood....

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Detalles Bibliográficos
Autores principales: Hagai, Tzachi, Chen, Xi, Miragaia, Ricardo J, Rostom, Raghd, Gomes, Tomás, Kunowska, Natalia, Henriksson, Johan, Park, Jong-Eun, Proserpio, Valentina, Donati, Giacomo, Bossini-Castillo, Lara, Vieira Braga, Felipe A, Naamati, Guy, Fletcher, James, Stephenson, Emily, Vegh, Peter, Trynka, Gosia, Kondova, Ivanela, Dennis, Mike, Haniffa, Muzlifah, Nourmohammad, Armita, Lässig, Michael, Teichmann, Sarah A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347972/
https://www.ncbi.nlm.nih.gov/pubmed/30356220
http://dx.doi.org/10.1038/s41586-018-0657-2

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