Cargando…

The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain

AIM: The aim of this study was to evaluate the prevalence of gastrointestinal disorders in non-cardiac chest pain (NCCP) Iranian patients. BACKGROUND: Gastro-esophageal reflux disease (GERD) is the most common cause of NCCP, which accounts for about one third of cases. METHODS: This was a descriptiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdi, Saeed, Sahraie, Roghayeh, Malekpour, Habib, Ashatri, Sara, Jahani-Sherafat, Somayeh, Iranshahi, Majid, Frootan, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347990/
https://www.ncbi.nlm.nih.gov/pubmed/30774805
_version_ 1783390029860569088
author Abdi, Saeed
Sahraie, Roghayeh
Malekpour, Habib
Ashatri, Sara
Jahani-Sherafat, Somayeh
Iranshahi, Majid
Frootan, Mojgan
author_facet Abdi, Saeed
Sahraie, Roghayeh
Malekpour, Habib
Ashatri, Sara
Jahani-Sherafat, Somayeh
Iranshahi, Majid
Frootan, Mojgan
author_sort Abdi, Saeed
collection PubMed
description AIM: The aim of this study was to evaluate the prevalence of gastrointestinal disorders in non-cardiac chest pain (NCCP) Iranian patients. BACKGROUND: Gastro-esophageal reflux disease (GERD) is the most common cause of NCCP, which accounts for about one third of cases. METHODS: This was a descriptive study on consecutive NCCP patients who referred to the gastroenterology clinic at the Taleghani Hospital, Tehran, Iran from 2015 to 2017. Medical history, physical examination and esophageal test including upper gastroenterology (UGI) endoscopy, esophageal manometry and 24 hour ambulatory esophageal pH monitoring were done for each participant. RESULTS: The study included 102 patients, of which 58.9% were women, and the mean age of patients was 41.5 ± 11.2 years. The most common symptoms associated with chest pain were regurgitation in 28.4%, dysphagia in 23.5% and heartburn in 19.6% patients. UGI endoscopy was abnormal in 29.4% cases, esophageal manometry was abnormal in 61.7% cases and ambulatory pH monitoring was abnormal in 37.2% patients. Using UGI endoscopy and combined 24-h pH monitoring determined the prevalence of GERD 44.1% , and based on manometry the most frequent causes of NCCP was ineffective esophageal motility (IEM) in 19.6% patients with NCCP. CONCLUSION: Detecting etiology of NCCP allows healthcare providers to assure patients of the benign nature of their condition and provide appropriate treatment. It can also help prevent excessive hospital and physician visits as well as the costly and potentially risky testing which often results.
format Online
Article
Text
id pubmed-6347990
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Shaheed Beheshti University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-63479902019-02-15 The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain Abdi, Saeed Sahraie, Roghayeh Malekpour, Habib Ashatri, Sara Jahani-Sherafat, Somayeh Iranshahi, Majid Frootan, Mojgan Gastroenterol Hepatol Bed Bench Original Article AIM: The aim of this study was to evaluate the prevalence of gastrointestinal disorders in non-cardiac chest pain (NCCP) Iranian patients. BACKGROUND: Gastro-esophageal reflux disease (GERD) is the most common cause of NCCP, which accounts for about one third of cases. METHODS: This was a descriptive study on consecutive NCCP patients who referred to the gastroenterology clinic at the Taleghani Hospital, Tehran, Iran from 2015 to 2017. Medical history, physical examination and esophageal test including upper gastroenterology (UGI) endoscopy, esophageal manometry and 24 hour ambulatory esophageal pH monitoring were done for each participant. RESULTS: The study included 102 patients, of which 58.9% were women, and the mean age of patients was 41.5 ± 11.2 years. The most common symptoms associated with chest pain were regurgitation in 28.4%, dysphagia in 23.5% and heartburn in 19.6% patients. UGI endoscopy was abnormal in 29.4% cases, esophageal manometry was abnormal in 61.7% cases and ambulatory pH monitoring was abnormal in 37.2% patients. Using UGI endoscopy and combined 24-h pH monitoring determined the prevalence of GERD 44.1% , and based on manometry the most frequent causes of NCCP was ineffective esophageal motility (IEM) in 19.6% patients with NCCP. CONCLUSION: Detecting etiology of NCCP allows healthcare providers to assure patients of the benign nature of their condition and provide appropriate treatment. It can also help prevent excessive hospital and physician visits as well as the costly and potentially risky testing which often results. Shaheed Beheshti University of Medical Sciences 2018 /pmc/articles/PMC6347990/ /pubmed/30774805 Text en ©2018 RIGLD, Research Institute for Gastroenterology and Liver Diseases This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Abdi, Saeed
Sahraie, Roghayeh
Malekpour, Habib
Ashatri, Sara
Jahani-Sherafat, Somayeh
Iranshahi, Majid
Frootan, Mojgan
The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain
title The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain
title_full The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain
title_fullStr The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain
title_full_unstemmed The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain
title_short The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain
title_sort high frequency of esophageal disorders in iranian patients with non-cardiac chest pain
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347990/
https://www.ncbi.nlm.nih.gov/pubmed/30774805
work_keys_str_mv AT abdisaeed thehighfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT sahraieroghayeh thehighfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT malekpourhabib thehighfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT ashatrisara thehighfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT jahanisherafatsomayeh thehighfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT iranshahimajid thehighfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT frootanmojgan thehighfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT abdisaeed highfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT sahraieroghayeh highfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT malekpourhabib highfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT ashatrisara highfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT jahanisherafatsomayeh highfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT iranshahimajid highfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain
AT frootanmojgan highfrequencyofesophagealdisordersiniranianpatientswithnoncardiacchestpain