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The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain
AIM: The aim of this study was to evaluate the prevalence of gastrointestinal disorders in non-cardiac chest pain (NCCP) Iranian patients. BACKGROUND: Gastro-esophageal reflux disease (GERD) is the most common cause of NCCP, which accounts for about one third of cases. METHODS: This was a descriptiv...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347990/ https://www.ncbi.nlm.nih.gov/pubmed/30774805 |
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author | Abdi, Saeed Sahraie, Roghayeh Malekpour, Habib Ashatri, Sara Jahani-Sherafat, Somayeh Iranshahi, Majid Frootan, Mojgan |
author_facet | Abdi, Saeed Sahraie, Roghayeh Malekpour, Habib Ashatri, Sara Jahani-Sherafat, Somayeh Iranshahi, Majid Frootan, Mojgan |
author_sort | Abdi, Saeed |
collection | PubMed |
description | AIM: The aim of this study was to evaluate the prevalence of gastrointestinal disorders in non-cardiac chest pain (NCCP) Iranian patients. BACKGROUND: Gastro-esophageal reflux disease (GERD) is the most common cause of NCCP, which accounts for about one third of cases. METHODS: This was a descriptive study on consecutive NCCP patients who referred to the gastroenterology clinic at the Taleghani Hospital, Tehran, Iran from 2015 to 2017. Medical history, physical examination and esophageal test including upper gastroenterology (UGI) endoscopy, esophageal manometry and 24 hour ambulatory esophageal pH monitoring were done for each participant. RESULTS: The study included 102 patients, of which 58.9% were women, and the mean age of patients was 41.5 ± 11.2 years. The most common symptoms associated with chest pain were regurgitation in 28.4%, dysphagia in 23.5% and heartburn in 19.6% patients. UGI endoscopy was abnormal in 29.4% cases, esophageal manometry was abnormal in 61.7% cases and ambulatory pH monitoring was abnormal in 37.2% patients. Using UGI endoscopy and combined 24-h pH monitoring determined the prevalence of GERD 44.1% , and based on manometry the most frequent causes of NCCP was ineffective esophageal motility (IEM) in 19.6% patients with NCCP. CONCLUSION: Detecting etiology of NCCP allows healthcare providers to assure patients of the benign nature of their condition and provide appropriate treatment. It can also help prevent excessive hospital and physician visits as well as the costly and potentially risky testing which often results. |
format | Online Article Text |
id | pubmed-6347990 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Shaheed Beheshti University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-63479902019-02-15 The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain Abdi, Saeed Sahraie, Roghayeh Malekpour, Habib Ashatri, Sara Jahani-Sherafat, Somayeh Iranshahi, Majid Frootan, Mojgan Gastroenterol Hepatol Bed Bench Original Article AIM: The aim of this study was to evaluate the prevalence of gastrointestinal disorders in non-cardiac chest pain (NCCP) Iranian patients. BACKGROUND: Gastro-esophageal reflux disease (GERD) is the most common cause of NCCP, which accounts for about one third of cases. METHODS: This was a descriptive study on consecutive NCCP patients who referred to the gastroenterology clinic at the Taleghani Hospital, Tehran, Iran from 2015 to 2017. Medical history, physical examination and esophageal test including upper gastroenterology (UGI) endoscopy, esophageal manometry and 24 hour ambulatory esophageal pH monitoring were done for each participant. RESULTS: The study included 102 patients, of which 58.9% were women, and the mean age of patients was 41.5 ± 11.2 years. The most common symptoms associated with chest pain were regurgitation in 28.4%, dysphagia in 23.5% and heartburn in 19.6% patients. UGI endoscopy was abnormal in 29.4% cases, esophageal manometry was abnormal in 61.7% cases and ambulatory pH monitoring was abnormal in 37.2% patients. Using UGI endoscopy and combined 24-h pH monitoring determined the prevalence of GERD 44.1% , and based on manometry the most frequent causes of NCCP was ineffective esophageal motility (IEM) in 19.6% patients with NCCP. CONCLUSION: Detecting etiology of NCCP allows healthcare providers to assure patients of the benign nature of their condition and provide appropriate treatment. It can also help prevent excessive hospital and physician visits as well as the costly and potentially risky testing which often results. Shaheed Beheshti University of Medical Sciences 2018 /pmc/articles/PMC6347990/ /pubmed/30774805 Text en ©2018 RIGLD, Research Institute for Gastroenterology and Liver Diseases This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Abdi, Saeed Sahraie, Roghayeh Malekpour, Habib Ashatri, Sara Jahani-Sherafat, Somayeh Iranshahi, Majid Frootan, Mojgan The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain |
title | The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain |
title_full | The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain |
title_fullStr | The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain |
title_full_unstemmed | The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain |
title_short | The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain |
title_sort | high frequency of esophageal disorders in iranian patients with non-cardiac chest pain |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347990/ https://www.ncbi.nlm.nih.gov/pubmed/30774805 |
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