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A new model of the mechanism underlying lead poisoning: SNP in miRNA target region influence the AGT expression level
BACKGROUND: To determine if the rs7079 polymorphism located in the 3′ UTR of the angiotensinogen gene (AGT) altered AGT gene expression and the risk of lead poisoning. A case-control study and luciferase reporter gene assay identified a significant association between rs7079 variants and the risk of...
Autores principales: | Wu, Yu, Wang, Miaomiao, Zhang, Jinlong, Sun, Na, Li, Chunping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348078/ https://www.ncbi.nlm.nih.gov/pubmed/30700972 http://dx.doi.org/10.1186/s41065-019-0084-x |
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