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PD-L1检测方法在非小细胞肺癌的研究进展
PD-1/PD-L1 inhibitors play an important role in the first-line and second-line treatment of non-small cell lung cancer (NSCLC), indicating a new treatment strategy of NSCLC. Completed clinical trials have shown that effective detection of PD-L1 expression is the key to the use of immunosuppressive a...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
Publicado: |
中国肺癌杂志编辑部
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348155/ https://www.ncbi.nlm.nih.gov/pubmed/30674392 http://dx.doi.org/10.3779/j.issn.1009-3419.2019.01.08 |
_version_ | 1783390040180654080 |
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collection | PubMed |
description | PD-1/PD-L1 inhibitors play an important role in the first-line and second-line treatment of non-small cell lung cancer (NSCLC), indicating a new treatment strategy of NSCLC. Completed clinical trials have shown that effective detection of PD-L1 expression is the key to the use of immunosuppressive agents. However, the gold standard for PD-L1 detection has still lacked. In recent years, immunohistochemistry (IHC) and enzyme-linked immunosorbent assay (ELISA) have been continuously innovated, which accounts for good prospect in PD-L1 detection. The research progress of PD-L1 detection methods in NSCLC is summarized in this review. |
format | Online Article Text |
id | pubmed-6348155 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | 中国肺癌杂志编辑部 |
record_format | MEDLINE/PubMed |
spelling | pubmed-63481552019-02-11 PD-L1检测方法在非小细胞肺癌的研究进展 Zhongguo Fei Ai Za Zhi 综述 PD-1/PD-L1 inhibitors play an important role in the first-line and second-line treatment of non-small cell lung cancer (NSCLC), indicating a new treatment strategy of NSCLC. Completed clinical trials have shown that effective detection of PD-L1 expression is the key to the use of immunosuppressive agents. However, the gold standard for PD-L1 detection has still lacked. In recent years, immunohistochemistry (IHC) and enzyme-linked immunosorbent assay (ELISA) have been continuously innovated, which accounts for good prospect in PD-L1 detection. The research progress of PD-L1 detection methods in NSCLC is summarized in this review. 中国肺癌杂志编辑部 2019-01-20 /pmc/articles/PMC6348155/ /pubmed/30674392 http://dx.doi.org/10.3779/j.issn.1009-3419.2019.01.08 Text en 版权所有©《中国肺癌杂志》编辑部2019 https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) License. See: https://creativecommons.org/licenses/by/3.0/ |
spellingShingle | 综述 PD-L1检测方法在非小细胞肺癌的研究进展 |
title | PD-L1检测方法在非小细胞肺癌的研究进展 |
title_full | PD-L1检测方法在非小细胞肺癌的研究进展 |
title_fullStr | PD-L1检测方法在非小细胞肺癌的研究进展 |
title_full_unstemmed | PD-L1检测方法在非小细胞肺癌的研究进展 |
title_short | PD-L1检测方法在非小细胞肺癌的研究进展 |
title_sort | pd-l1检测方法在非小细胞肺癌的研究进展 |
topic | 综述 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348155/ https://www.ncbi.nlm.nih.gov/pubmed/30674392 http://dx.doi.org/10.3779/j.issn.1009-3419.2019.01.08 |
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