Cargando…

The Distinct Effects of Palmitic and Oleic Acid on Pancreatic Beta Cell Function: The Elucidation of Associated Mechanisms and Effector Molecules

In this study, we aimed to identify the mechanisms underlying the different effects of palmitic acid and oleic acid on human pancreatic beta cell function. To address this problem, the oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis and their mediator molecules have been inve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nemecz, Miruna, Constantin, Alina, Dumitrescu, Madalina, Alexandru, Nicoleta, Filippi, Alexandru, Tanko, Gabriela, Georgescu, Adriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348268/ https://www.ncbi.nlm.nih.gov/pubmed/30719005 http://dx.doi.org/10.3389/fphar.2018.01554

Ejemplares similares

Extracellular Vesicles from Adipose Tissue Stem Cells in Diabetes and Associated Cardiovascular Disease; Pathobiological Impact and Therapeutic Potential
por: Constantin, Alina, et al.
Publicado: (2020)

Role of MicroRNA in Endothelial Dysfunction and Hypertension
por: Nemecz, Miruna, et al.
Publicado: (2016)

Platelets of Healthy Origins Promote Functional Improvement of Atherosclerotic Endothelial Progenitor Cells
por: Alexandru, Nicoleta, et al.
Publicado: (2019)

Hypertension Associated With Hyperlipidemia Induced Different MicroRNA Expression Profiles in Plasma, Platelets, and Platelet-Derived Microvesicles; Effects of Endothelial Progenitor Cell Therapy
por: Alexandru, Nicoleta, et al.
Publicado: (2019)

Hypertension induces compensatory left ventricular hypertrophy by a mechanism involving gap junction lateralization and overexpression of CD36, PKC and MMP-2
por: Dumitrescu, Mădălina, et al.
Publicado: (2021)

Stem cell‐derived extracellular vesicles reduce the expression of molecules involved in cardiac hypertrophy—In a model of human-induced pluripotent stem cell-derived cardiomyocytes
por: Constantin, Alina, et al.
Publicado: (2022)

Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles on Atherosclerosis-Induced Vascular Dysfunction and Its Key Molecular Players
por: Comariţa, Ioana Karla, et al.
Publicado: (2022)

Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential
por: Nemecz, Miruna, et al.
Publicado: (2023)

Integrins α4β1 and αVβ3 are Reduced in Endothelial Progenitor Cells from Diabetic Dyslipidemic Mice and May Represent New Targets for Therapy in Aortic Valve Disease
por: Filippi, Alexandru, et al.
Publicado: (2020)

VLA4-Enhanced Allogeneic Endothelial Progenitor Cell-Based Therapy Preserves the Aortic Valve Function in a Mouse Model of Dyslipidemia and Diabetes
por: Filippi, Alexandru, et al.
Publicado: (2022)

Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
por: Zeng, Xin, et al.
Publicado: (2020)

Physiological Doses of Oleic and Palmitic Acids Protect Human Endothelial Cells from Oxidative Stress
por: Palomino, Olga M., et al.
Publicado: (2022)

Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis
por: Tucureanu, Monica Madalina, et al.
Publicado: (2019)

Inactivation of Salmonella spp. and Listeria spp. by Palmitic, Stearic, and Oleic Acid Sophorolipids and Thiamine Dilauryl Sulfate
por: Zhang, Xuejie, et al.
Publicado: (2016)

Correction to: Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
por: Zeng, Xin, et al.
Publicado: (2020)

Palmitic Acid and Oleic Acid Differently Modulate TLR2-Mediated Inflammatory Responses in Microglia and Macrophages
por: Howe, Anne-Marie, et al.
Publicado: (2022)

Sex-Dependent Regulation of Placental Oleic Acid and Palmitic Acid Metabolism by Maternal Glycemia and Associations with Birthweight
por: Watkins, Oliver C., et al.
Publicado: (2022)

Exposure to dietary fatty acids oleic and palmitic acid alters structure and mechanotransduction of intestinal cells in vitro
por: Bergen, Janice, et al.
Publicado: (2023)

The Different Mechanisms of Lipid Accumulation in Hepatocytes Induced by Oleic Acid/Palmitic Acid and High-Fat Diet
por: Zhang, Miao, et al.
Publicado: (2023)

Circulating Endothelial Progenitor Cell and Platelet Microparticle Impact on Platelet Activation in Hypertension Associated with Hypercholesterolemia
por: Alexandru, Nicoleta, et al.
Publicado: (2013)

Microvesicles and Microvesicle-Associated microRNAs Reflect Glioblastoma Regression: Microvesicle-Associated miR-625-5p Has Biomarker Potential
por: Simionescu, Natalia, et al.
Publicado: (2022)

Palmitate induces DNA damage and senescence in human adipocytes in vitro that can be alleviated by oleic acid but not inorganic nitrate
por: Ishaq, Abbas, et al.
Publicado: (2022)

Oleic Acid and Palmitic Acid from Bacteroides thetaiotaomicron and Lactobacillus johnsonii Exhibit Anti-Inflammatory and Antifungal Properties
por: Charlet, Rogatien, et al.
Publicado: (2022)

Ocular Complications of Radiotherapy in Uveal Melanoma
por: Zemba, Mihail, et al.
Publicado: (2023)

Differential Effects of Oleic and Palmitic Acids on Lipid Droplet-Mitochondria Interaction in the Hepatic Cell Line HepG2
por: Eynaudi, Andrea, et al.
Publicado: (2021)

Free fatty acid treatment of mouse preimplantation embryos demonstrates contrasting effects of palmitic acid and oleic acid on autophagy
por: Leung, Zuleika C. L., et al.
Publicado: (2022)

Protective Effects of Oleic Acid Against Palmitic Acid-Induced Apoptosis in Pancreatic AR42J Cells and Its Mechanisms
por: Ahn, Joung Hoon, et al.
Publicado: (2013)

Oleic acid ameliorates palmitic acid-induced ER stress and inflammation markers in naive and cerulein-treated exocrine pancreas cells
por: Ben-Dror, Karin, et al.
Publicado: (2019)

Exogenous Oleic Acid and Palmitic Acid Improve Boar Sperm Motility via Enhancing Mitochondrial Β-Oxidation for ATP Generation
por: Zhu, Zhendong, et al.
Publicado: (2020)

Biomarkers of ocular allergy and dry eye disease
por: Zemba, Mihail, et al.
Publicado: (2023)

Inflammatory markers in acute myocardial infarction and the correlation with the severity of coronary heart disease
por: Oprescu, Nicoleta, et al.
Publicado: (2021)

Efficient biodiesel production from oleic and palmitic acid using a novel molybdenum metal–organic framework as efficient and reusable catalyst
por: Ghorbani-Choghamarani, Arash, et al.
Publicado: (2022)

Utilization of vanillin to prepare sulfated Calix[4]resorcinarene as efficient organocatalyst for biodiesel production based on methylation of palmitic acid and oleic acid
por: Jumina, Jumina, et al.
Publicado: (2023)

Intravenous Administration of Allogenic Cell-Derived Microvesicles of Healthy Origins Defends Against Atherosclerotic Cardiovascular Disease Development by a Direct Action on Endothelial Progenitor Cells
por: Alexandru, Nicoleta, et al.
Publicado: (2020)

Oleic Acid Counters Impaired Blastocyst Development Induced by Palmitic Acid During Mouse Preimplantation Development: Understanding Obesity-Related Declines in Fertility
por: Yousif, Maisoon D., et al.
Publicado: (2020)

Systematic Investigation of Co-Crystallization Properties in Binary and Ternary Mixtures of Triacylglycerols Containing Palmitic and Oleic Acids in Relation with Palm Oil Dry Fractionation
por: Gibon, Veronique, et al.
Publicado: (2020)

T cells cooperate with palmitic acid in induction of beta cell apoptosis
por: Cvjetićanin, Tamara, et al.
Publicado: (2009)

Distinct metabolic patterns during microglial remodeling by oleate and palmitate
por: Chausse, Bruno, et al.
Publicado: (2019)

Characterization of a novel sn1,3 lipase from Ricinus communis L. suitable for production of oleic acid-palmitic acid-glycerol oleate
por: Li, Yue, et al.
Publicado: (2021)

Double-Controlled Release of Poorly Water-Soluble Paliperidone Palmitate from Self-Assembled Albumin-Oleic Acid Nanoparticles in PLGA in situ Forming Implant
por: Yu, Yongjun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pch4imvrbuc71d49jppo30fcj7