Cargando…

Direct free radical scavenging effects of water-soluble HMG-CoA reductase inhibitors

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, statins, are widely used for preventing cardiovascular and cerebrovascular diseases by controlling blood cholesterol level. Additionally, previous studies revealed the scavenging effects of statins on free radicals. We assessed direct scave...

Descripción completa

Detalles Bibliográficos
Autores principales:	Umeda, Ryohei, Takanari, Hiroki, Ogata, Kazue, Matsumoto, Shigekiyo, Kitano, Takaaki, Ono, Katsushige, Tokumaru, Osamu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	the Society for Free Radical Research Japan 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348410/ https://www.ncbi.nlm.nih.gov/pubmed/30705508 http://dx.doi.org/10.3164/jcbn.18-48

Ejemplares similares

The dose-response relationships of the direct scavenging activity of amide-based local anesthetics against multiple free radicals
por: Sato, Yukiko, et al.
Publicado: (2023)

Dose-dependent scavenging activity of the ultra-short-acting β1-blocker landiolol against specific free radicals
por: Matsumoto, Shigekiyo, et al.
Publicado: (2022)

Predictive Modeling of HMG-CoA Reductase Inhibitory Activity and Design of New HMG-CoA Reductase Inhibitors
por: Samizo, Shigeyoshi, et al.
Publicado: (2023)

Pleiotropic effects of the HMG-CoA reductase inhibitors
por: Mihos, Christos G, et al.
Publicado: (2011)

Optimization of Ultrasonic-Assisted Extraction of Total Phenolics from Citrus aurantium L. Blossoms and Evaluation of Free Radical Scavenging, Anti-HMG-CoA Reductase Activities
por: Hao, Kexin, et al.
Publicado: (2019)

The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation
por: Gelosa, Paolo, et al.
Publicado: (2007)

Positive pleiotropic effects of HMG-CoA reductase inhibitor on vitiligo
por: Noël, Martin, et al.
Publicado: (2004)

Structural and functional characterization of HMG-COA reductase from Artemisia annua
por: Kiran, Usha, et al.
Publicado: (2010)

Transcription of the three HMG-CoA reductase genes of Mucor circinelloides
por: Nagy, Gábor, et al.
Publicado: (2014)

Functional Implications of HMG-CoA Reductase Inhibition on Glucose Metabolism
por: Han, Ki Hoon
Publicado: (2018)

Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy
por: Lorenzo-Villalba, Noel, et al.
Publicado: (2021)

Eupatilin Alleviates Hyperlipidemia in Mice by Inhibiting HMG-CoA Reductase
por: Kim, Kyung-Joo, et al.
Publicado: (2023)

Are Point Mutations in HMG-CoA Reductases (Hmg1 and Hmg2) a Step towards Azole Resistance in Aspergillus fumigatus?
por: Gonzalez-Jimenez, Irene, et al.
Publicado: (2021)

The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases
por: Friesen, Jon A, et al.
Publicado: (2004)

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase
por: Würtz, Peter, et al.
Publicado: (2016)

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase
por: Schumacher, Marc M, et al.
Publicado: (2015)

Degradation of HMG-CoA reductase-induced membranes in the fission yeast, Schizosaccharomyces pombe
Publicado: (1995)

Role of HMG-CoA reductase inhibitors with curative radiotherapy in men with prostate cancer
por: Solanki, Abhishek A, et al.
Publicado: (2011)

Lepidopteran HMG-CoA reductase is a potential selective target for pest control
por: Li, Yuan-mei, et al.
Publicado: (2017)

HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival
por: Lacher, Sonja M, et al.
Publicado: (2017)

An Atomic-Level Perspective of HMG-CoA-Reductase: The Target Enzyme to Treat Hypercholesterolemia
por: Gesto, Diana S., et al.
Publicado: (2020)

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition
por: Kettunen, Johannes, et al.
Publicado: (2019)

Targeting Enterococcus faecalis HMG-CoA reductase with a non-statin inhibitor
por: Bose, Sucharita, et al.
Publicado: (2023)

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol
por: Jiang, Shi-You, et al.
Publicado: (2018)

HMG CoA reductase inhibitors (statins) to treat Epstein–Barr virus-driven lymphoma
por: Cohen, J I
Publicado: (2005)

Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast
Publicado: (1994)

Association between Use of HMG CoA Reductase Inhibitors and Mortality in HIV-Infected Patients
por: Moore, Richard D., et al.
Publicado: (2011)

Prognostic impact of tumour-specific HMG-CoA reductase expression in primary breast cancer
por: Borgquist, Signe, et al.
Publicado: (2008)

Antihyperlipidemic Activity of Aloe succotrina in Rats: Possibly Mediated by Inhibition of HMG-CoA Reductase
por: Dhingra, Dinesh, et al.
Publicado: (2014)

Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system
por: Tsai, Yien Che, et al.
Publicado: (2012)

Development of Clinical Data Mart of HMG-CoA Reductase Inhibitor for Varied Clinical Research
por: Kim, Hun-Sung, et al.
Publicado: (2017)

Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition
por: Kettunen, Johannes, et al.
Publicado: (2020)

Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver
por: Zhong, Shanshan, et al.
Publicado: (2021)

Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain
por: Chen, Hongwen, et al.
Publicado: (2022)

Use of HMG-CoA Reductase Inhibitors in the HIV Population: Implications for Individualized Treatment Selection
por: Advani, Ashish, et al.
Publicado: (2014)

HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis
por: Palmer, Suetonia C., et al.
Publicado: (2015)

HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis
por: Palmer, Suetonia C., et al.
Publicado: (2014)

Chronic Anti-HMG-CoA Reductase Positive Necrotizing Myositis With Remote Exposure to Statins
por: Salar, Tooba, et al.
Publicado: (2023)

Modulation of Dendritic Cell Immunobiology via Inhibition of 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) Reductase
por: Leuenberger, Tina, et al.
Publicado: (2014)

HMG-CoA reductase is regulated by environmental salinity and its activity is essential for halotolerance in halophilic fungi
por: Vaupotič, T., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_ac9puiqhqm0g4nvc00qkeauuev