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Mitochondrial stress response triggered by defects in protein synthesis quality control
Mitochondria have a compartmentalized gene expression system dedicated to the synthesis of membrane proteins essential for oxidative phosphorylation. Responsive quality control mechanisms are needed to ensure that aberrant protein synthesis does not disrupt mitochondrial function. Pathogenic mutatio...
Autores principales: | Richter, Uwe, Ng, Kah Ying, Suomi, Fumi, Marttinen, Paula, Turunen, Taina, Jackson, Christopher, Suomalainen, Anu, Vihinen, Helena, Jokitalo, Eija, Nyman, Tuula A, Isokallio, Marita A, Stewart, James B, Mancini, Cecilia, Brusco, Alfredo, Seneca, Sara, Lombès, Anne, Taylor, Robert W, Battersby, Brendan J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348486/ https://www.ncbi.nlm.nih.gov/pubmed/30683687 http://dx.doi.org/10.26508/lsa.201800219 |
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