PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework

We present the case of a man with oligometastatic prostate cancer who underwent a PSMA-targeted 18F-DCFPyL PET/CT scan in order to illustrate how the PSMA-RADS grading sytem can be successfully used to support clinical decision-making and treatment planning. Notably, the presented patient was found...

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Detalles Bibliográficos
Autores principales: Reyes, Diane K., Demehri, Shadpour, Werner, Rudolf A., Pomper, Martin G., Gorin, Michael A., Rowe, Steven P., Pienta, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348696/
https://www.ncbi.nlm.nih.gov/pubmed/30705827
http://dx.doi.org/10.1016/j.eucr.2019.01.007
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author Reyes, Diane K.
Demehri, Shadpour
Werner, Rudolf A.
Pomper, Martin G.
Gorin, Michael A.
Rowe, Steven P.
Pienta, Kenneth J.
author_facet Reyes, Diane K.
Demehri, Shadpour
Werner, Rudolf A.
Pomper, Martin G.
Gorin, Michael A.
Rowe, Steven P.
Pienta, Kenneth J.
author_sort Reyes, Diane K.
collection PubMed
description We present the case of a man with oligometastatic prostate cancer who underwent a PSMA-targeted 18F-DCFPyL PET/CT scan in order to illustrate how the PSMA-RADS grading sytem can be successfully used to support clinical decision-making and treatment planning. Notably, the presented patient was found to have an equivocal bone lesion (PSMA-RADS-3B) which was further worked up with a tumor protocol MRI and found to be definitively benign (PSMA-RADS-1B) and thus removed from the oligometastatic treatment plan. Remaining avid lesions were incorporated into the treatment plan or deferred for later work-up or monitoring, as indicated within the PSMA-RADS framework.
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spelling pubmed-63486962019-01-31 PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework Reyes, Diane K. Demehri, Shadpour Werner, Rudolf A. Pomper, Martin G. Gorin, Michael A. Rowe, Steven P. Pienta, Kenneth J. Urol Case Rep Oncology We present the case of a man with oligometastatic prostate cancer who underwent a PSMA-targeted 18F-DCFPyL PET/CT scan in order to illustrate how the PSMA-RADS grading sytem can be successfully used to support clinical decision-making and treatment planning. Notably, the presented patient was found to have an equivocal bone lesion (PSMA-RADS-3B) which was further worked up with a tumor protocol MRI and found to be definitively benign (PSMA-RADS-1B) and thus removed from the oligometastatic treatment plan. Remaining avid lesions were incorporated into the treatment plan or deferred for later work-up or monitoring, as indicated within the PSMA-RADS framework. Elsevier 2019-01-09 /pmc/articles/PMC6348696/ /pubmed/30705827 http://dx.doi.org/10.1016/j.eucr.2019.01.007 Text en © 2019 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Reyes, Diane K.
Demehri, Shadpour
Werner, Rudolf A.
Pomper, Martin G.
Gorin, Michael A.
Rowe, Steven P.
Pienta, Kenneth J.
PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework
title PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework
title_full PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework
title_fullStr PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework
title_full_unstemmed PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework
title_short PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework
title_sort psma-targeted [(18)f]dcfpyl pet/ct-avid lesions in a patient with prostate cancer: clinical decision-making informed by the psma-rads interpretive framework
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348696/
https://www.ncbi.nlm.nih.gov/pubmed/30705827
http://dx.doi.org/10.1016/j.eucr.2019.01.007
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