Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion

Lamotrigine is a new generation antiepileptic which blocks sodium channels and can cause significant toxicity in overdose. A case of a three-year-old child who suffered a seizure and required endotracheal intubation after accidental lamotrigine ingestion is presented. The lamotrigine concentration m...

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Autores principales: Griswold, Ashley, Tully, Briana, Katz, Kenneth, Beauchamp, Gillian, Cook, Matthew, Cannon, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348928/
https://www.ncbi.nlm.nih.gov/pubmed/30755805
http://dx.doi.org/10.1155/2019/2675931
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author Griswold, Ashley
Tully, Briana
Katz, Kenneth
Beauchamp, Gillian
Cook, Matthew
Cannon, Robert
author_facet Griswold, Ashley
Tully, Briana
Katz, Kenneth
Beauchamp, Gillian
Cook, Matthew
Cannon, Robert
author_sort Griswold, Ashley
collection PubMed
description Lamotrigine is a new generation antiepileptic which blocks sodium channels and can cause significant toxicity in overdose. A case of a three-year-old child who suffered a seizure and required endotracheal intubation after accidental lamotrigine ingestion is presented. The lamotrigine concentration measured 23.2 mcg/mL which is the highest reported after accidental pediatric exposure. A review of the literature regarding pediatric lamotrigine poisoning is also included.
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spelling pubmed-63489282019-02-12 Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion Griswold, Ashley Tully, Briana Katz, Kenneth Beauchamp, Gillian Cook, Matthew Cannon, Robert Case Rep Emerg Med Case Report Lamotrigine is a new generation antiepileptic which blocks sodium channels and can cause significant toxicity in overdose. A case of a three-year-old child who suffered a seizure and required endotracheal intubation after accidental lamotrigine ingestion is presented. The lamotrigine concentration measured 23.2 mcg/mL which is the highest reported after accidental pediatric exposure. A review of the literature regarding pediatric lamotrigine poisoning is also included. Hindawi 2019-01-13 /pmc/articles/PMC6348928/ /pubmed/30755805 http://dx.doi.org/10.1155/2019/2675931 Text en Copyright © 2019 Ashley Griswold et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Griswold, Ashley
Tully, Briana
Katz, Kenneth
Beauchamp, Gillian
Cook, Matthew
Cannon, Robert
Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion
title Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion
title_full Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion
title_fullStr Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion
title_full_unstemmed Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion
title_short Lamotrigine ODT-Induced Seizure in a 3-Year-Old Child after Accidental Ingestion
title_sort lamotrigine odt-induced seizure in a 3-year-old child after accidental ingestion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348928/
https://www.ncbi.nlm.nih.gov/pubmed/30755805
http://dx.doi.org/10.1155/2019/2675931
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