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Mechanism and physiological significance of autoregulation of the Escherichia coli hfq gene

The RNA chaperone Hfq plays a critical role in sRNA-mediated gene regulation in enteric bacteria. The major role of Hfq is to stimulate base-pairing between sRNAs and target mRNAs by binding both RNAs through three RNA-binding surfaces. To understand the post-transcriptional network exerted by Hfq a...

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Detalles Bibliográficos
Autores principales: Morita, Teppei, Aiba, Hiroji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348989/
https://www.ncbi.nlm.nih.gov/pubmed/30487269
http://dx.doi.org/10.1261/rna.068106.118