Cargando…

Nucleobase carbonyl groups are poor Mg(2+) inner-sphere binders but excellent monovalent ion binders—a critical PDB survey

Precise knowledge of Mg(2+) inner-sphere binding site properties is vital for understanding the structure and function of nucleic acid systems. Unfortunately, the PDB, which represents the main source of Mg(2+) binding sites, contains a substantial number of assignment issues that blur our understan...

Descripción completa

Detalles Bibliográficos
Autores principales: Leonarski, Filip, D'Ascenzo, Luigi, Auffinger, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348993/
https://www.ncbi.nlm.nih.gov/pubmed/30409785
http://dx.doi.org/10.1261/rna.068437.118