Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis

Severe aplastic anemia (SAA) is a hematological disease resulting in pancytopenia due to bone marrow failure. Treatment consists of immunosppressive therapy, or allo-SCT. Patients with aplastic anemia are predisposed to invasive fungal infections due to mucormycosis. Till now, syngeneic SCT in the c...

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Autores principales: El-Cheikh, Jean, Atoui, Ali, Moukalled, Nour, Ghaoui, Nohra, El Darsa, Haidar, Kanj, Souha S., Bazarbachi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349008/
https://www.ncbi.nlm.nih.gov/pubmed/30705813
http://dx.doi.org/10.1016/j.mmcr.2019.01.001
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author El-Cheikh, Jean
Atoui, Ali
Moukalled, Nour
Ghaoui, Nohra
El Darsa, Haidar
Kanj, Souha S.
Bazarbachi, Ali
author_facet El-Cheikh, Jean
Atoui, Ali
Moukalled, Nour
Ghaoui, Nohra
El Darsa, Haidar
Kanj, Souha S.
Bazarbachi, Ali
author_sort El-Cheikh, Jean
collection PubMed
description Severe aplastic anemia (SAA) is a hematological disease resulting in pancytopenia due to bone marrow failure. Treatment consists of immunosppressive therapy, or allo-SCT. Patients with aplastic anemia are predisposed to invasive fungal infections due to mucormycosis. Till now, syngeneic SCT in the context of active mucormycosis infection for patients with severe aplastic anemia is lacking in the literature. Here, we report a case of severe aplastic anemia with disseminated mucormycosis infection undergoing syngeneic transplant.
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spelling pubmed-63490082019-01-31 Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis El-Cheikh, Jean Atoui, Ali Moukalled, Nour Ghaoui, Nohra El Darsa, Haidar Kanj, Souha S. Bazarbachi, Ali Med Mycol Case Rep Case Report Severe aplastic anemia (SAA) is a hematological disease resulting in pancytopenia due to bone marrow failure. Treatment consists of immunosppressive therapy, or allo-SCT. Patients with aplastic anemia are predisposed to invasive fungal infections due to mucormycosis. Till now, syngeneic SCT in the context of active mucormycosis infection for patients with severe aplastic anemia is lacking in the literature. Here, we report a case of severe aplastic anemia with disseminated mucormycosis infection undergoing syngeneic transplant. Elsevier 2019-01-12 /pmc/articles/PMC6349008/ /pubmed/30705813 http://dx.doi.org/10.1016/j.mmcr.2019.01.001 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
El-Cheikh, Jean
Atoui, Ali
Moukalled, Nour
Ghaoui, Nohra
El Darsa, Haidar
Kanj, Souha S.
Bazarbachi, Ali
Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis
title Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis
title_full Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis
title_fullStr Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis
title_full_unstemmed Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis
title_short Successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis
title_sort successful treatment of severe aplastic anemia with syngeneic stem cell transplantation in the setting of active disseminated mucormycosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349008/
https://www.ncbi.nlm.nih.gov/pubmed/30705813
http://dx.doi.org/10.1016/j.mmcr.2019.01.001
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