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NP220 mediates silencing of unintegrated retroviral DNA
The entry of foreign DNA into many mammalian cell types triggers the innate immune system, a complex set of responses directed at preventing infection by pathogens. One aspect of the response is the potent epigenetic silencing of incoming viral DNAs(1), including the extrachromosomal DNAs formed imm...
Autores principales: | Zhu, Yiping, Wang, Gary Z., Cingöz, Oya, Goff, Stephen P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349045/ https://www.ncbi.nlm.nih.gov/pubmed/30487602 http://dx.doi.org/10.1038/s41586-018-0750-6 |
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