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The anti-apoptotic proteins NAF-1 and iASPP interact to drive apoptosis in cancer cells
Suppression of apoptosis is a key Hallmark of cancer cells, and reactivation of apoptosis is a major avenue for cancer therapy. We reveal an interaction between the two anti-apoptotic proteins iASPP and NAF-1, which are overexpressed in many types of cancer cells and tumors. iASPP is an inhibitory m...
Autores principales: | Iosub-Amir, Anat, Bai, Fang, Sohn, Yang-Sung, Song, Luhua, Tamir, Sagi, Marjault, Henri-Baptiste, Mayer, Guy, Karmi, Ola, Jennings, Patricia A., Mittler, Ron, Onuchic, José N., Friedler, Assaf, Nechushtai, Rachel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349067/ https://www.ncbi.nlm.nih.gov/pubmed/30774867 http://dx.doi.org/10.1039/c8sc03390k |
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