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Lytic reactions of drugs with lipid membranes

Propranolol is shown to undergo lipidation reactions in three types of lipid membrane: (1) synthetic single-component glycerophospholipid liposomes; (2) liposomes formed from complex lipid mixtures extracted from E. coli or liver cells; and (3) in cellulo in Hep G2 cells. Fourteen different lipidate...

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Detalles Bibliográficos
Autores principales: Britt, Hannah M., García-Herrero, Clara A., Denny, Paul W., Mosely, Jackie A., Sanderson, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349070/
https://www.ncbi.nlm.nih.gov/pubmed/30774868
http://dx.doi.org/10.1039/c8sc04831b